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Набор скоро начнётся NCT07741591

Impact of Perioperative Antibiotic Use on Surgical Scarring

— Наблюдательное Surgical Scar Postoperative Scar

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Perioperative Antibiotic Exposure.
Кому может быть актуально
Состояния в реестре: Surgical Scar, Postoperative Scar. Базовые параметры: от 18 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Китай
Следующий шаг
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Официальное название

Perioperative Antibiotic Use and Its Impact on Postoperative Scarring: A Retrospective Study

Обзор

This retrospective observational cohort study will evaluate whether perioperative antibiotic use is associated with long-term surgical scar outcomes. The study will include adult patients who underwent body surface surgery at Nanfang Hospital between January 1, 2005 and January 1, 2025 and have available surgical, medication, and scar-related clinical records. The study will not assign participants to any treatment. Researchers will review existing medical records, perioperative antibiotic exposure, surgical characteristics, complications, and scar assessments or photographs. Scar outcomes will be assessed using modified visual analogue scale scores, scar width, scar type, and scar-related complications.

Вмешательства

  • Другое Perioperative Antibiotic Exposure
    Patterns of perioperative antibiotic use documented in existing medical records, including timing, indication, antibiotic type, duration, frequency, and route of administration. No antibiotic treatment will be assigned or provided by the study.

Первичные конечные точки

  • Overall Scar Appearance Score Assessed Using a Modified Visual Analogue Scale [Срок оценки: Scar photographs were taken during postoperative clinical follow-up, with an overall range from 3 months to 20 years after surgery. Given the wide span, the assessments will be stratified and reported according to the actual time of photography, for exam]
Вторичные конечные точки (4)
  • Scar Color Score Assessed Using a Modified Visual Analogue Scale [Срок оценки: Scar photographs were taken during postoperative clinical follow-up, with an overall range from 3 months to 20 years after surgery. Given the wide span, the assessments will be stratified and reported according to the actual time of photography, for exam]
  • Scar Texture Score Assessed Using a Modified Visual Analogue Scale [Срок оценки: Scar photographs were taken during postoperative clinical follow-up, with an overall range from 3 months to 20 years after surgery. Given the wide span, the assessments will be stratified and reported according to the actual time of photography, for exam]
  • Scar Width [Срок оценки: Scar photographs were taken during postoperative clinical follow-up, with an overall range from 3 months to 20 years after surgery. Given the wide span, the assessments will be stratified and reported according to the actual time of photography, for exam]
  • Scar-Related Complications [Срок оценки: Postoperative days 0 to 30 (inclusive). The timing of each complication was determined from medical records.]

Критерии участия

Критерии включения

  • Age 18 years or older.
  • Underwent body surface surgery at Nanfang Hospital between January 1, 2005 and January 1, 2025, with a linear surgical incision scar.
  • Presented to the Department of Plastic Surgery at Nanfang Hospital for surgical scar-related care.
  • Had no medical encounter record at Nanfang Hospital from January 1, 2025 to the time of study screening.
  • Available clear surgical records and perioperative medication records.

Критерии исключения

  • Known tendency for pathological scarring or scar constitution.
  • History of chronic skin disease in the surgical area, such as psoriasis or eczema.
  • Uncontrolled diabetes mellitus, malnutrition, hypoalbuminemia, or long-term use of immunosuppressive agents or glucocorticoids.
  • Target scar received any scar-specific treatment after surgery, such as laser therapy, radiotherapy, drug injection, or surgical revision.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения
Когортное

Центры проведения

Китай · 1 центр
  • Nanfang Hospital, Southern Medical University — Гуанчжоу

Идентификаторы

NCT: NCT07741591 · NFEC-2026-164 · MR-44-26-022534

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗