Efficacy of Seated Exercise on Functional Capacity and Quality of Life in Patients With Leukemia During Chemotherapy Cycles

Обзор

This study aims to evaluate the efficacy of seated exercise on functional capacity and quality of life in patients with leukemia during chemotherapy cycles Participants will receive efficacy of seated exercise on functional capacity and quality of life in patients with leukemia during chemotherapy cycles over a defined period. Outcomes will be assessed using Pulmonary function test, 6 min walk test and FACT- G questionnaire to determine improvements in quality of life in cancer patient rehabilitation special to diagnosed with leukemia.

Подробное описание

Cancer is a major public health that gives an economical burden on the patient and government. The incidence of different types of cell tumors are increasing nowadays. Although chemotherapy is given to kill cancer cells, it also damage normal cells and cause significant side effects while others may have more. Some CT side effects can be severe enough to require hospitalization effects. CT affects patients functional capacity and quality of life next to the cancer it self. This study is designed as randomized controlled trial to assess the impact of seated exercise on functional capacity and quality of life in patient with leukemia during chemotherapy cycles. participants will be recruited from National Cancer Institute.

The intervention protocol includes a-30 minutes seated exercise program three times a week with at least a one- day break between sessions for four weeks for the treatment group. Outcome measures will include maximum voluntary ventilation, 6 min walk test distance and FACT-G questionnaire before and after the exercise program. The program includes a five- minute warmup, 20 minutes of moderate-intensity repetitive motion exercise and a five- minute cool down.

Ethical considerations:

This study has been reviewed and approved by the Ethical Committee of Benha university. Written informed consent will be obtained from all participants or their legal guardians prior to treatment.

Вмешательства

• Поведенческое Seated exercise
  Participants in the intervention group will perform a structured seated exercise program during their chemotherapy cycles. The exercise program will consist of supervised, individualized seated exercises designed to improve functional capacity and quality of life. The exercise sessions will be performed according to the study protocol throughout the intervention period. Each session will consist of a five-minute warm up, 20 minutes of moderate intensity repetitive motion exercises, and a five -

Первичные конечные точки

• change in functional capacity [Срок оценки: Baseline and after 4 weeks of intervention]
• change in quality of life [Срок оценки: Baseline and after 4 weeks of intervention]

Вторичные конечные точки (1)

• Change in Maximum Voluntary Ventilation (MVV) [Срок оценки: Baseline and after 4 weeks of intervention]

Критерии участия

Критерии включения

• Male patients with age ranges from 30 to 40 years.
• All patients in this study will be on chemotherapy from at least one cycle as a treatment of leukemia.
• All patients will be hemodynamically stable.
• Patients are ambulant.

Критерии исключения

• Lung cancer
• History of any pulmonary disease.
• Metastasis of lung , ribs and mediastinal structure.
• Pulmonary pathology (e.g. acute respiratory distress syndrome, or exacerbation of chronic obstructive pulmonary disease).
• Ruptured eardrum or any other condition of the ear.
• Severe bronchospasm.
• High peak air way pressure (barotraumas).
• patients with marked elevated left ventricular end- diastolic volume and pressure.
• patients with worsening haert failure signs and symptoms.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT07740174 · seated exercises in leukemia

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗