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Идёт набор NCT07725003

Telerehabilitation Based Motor Relearning Program and Telerehabilitation Based Conventional Physical Therapy in Stroke

Без фазы С лечением Stroke

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Telerehabilitation Based Motor Relearning Program, Conventional physical therapy.
Кому может быть актуально
Состояния в реестре: Stroke. Базовые параметры: 40 лет — 70 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Пакистан
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
Официальное название

Comparative Effects of Telerehabilitation Based Motor Relearning Program and Telerehabilitation Based Conventional Physical Therapy on Motor Function and Balance in Stroke Patients.

Обзор

This study aims to compare the effects of telerehabilitation based motor relearning program and telerehabilitation based conventional physical therapy on motor function and balance in stroke patients.

Подробное описание

Several recent studies have demonstrated the effectiveness of telerehabilitation in stroke rehabilitation. An umbrella review published in 2024 evaluated systematic reviews and meta-analyses conducted between 2010 and 2023 and concluded that telerehabilitation is effective in enhancing mobility, upper limb function, and balance in post-stroke patients. The review also emphasized the technology's role in increasing access to rehabilitation services and reducing treatment delays, especially in rural or underserved areas. The findings support the integration of telerehabilitation into standard stroke care practices.

A randomized controlled trial conducted in 2023 on 60 post-stroke patients compared home-based telerehabilitation with traditional outpatient therapy over an 8-week period. Participants in both groups demonstrated significant improvements in the Berg Balance Scale (BBS) and Fugl-Meyer Assessment (FMA) scores. However, the telerehabilitation group reported slightly higher patient satisfaction and adherence, indicating that home-based telerehabilitation is a feasible and effective alternative for improving motor function and balance in stroke survivors.

A longitudinal observational study published in 2022 involving 120 individuals in the subacute and chronic phases of stroke recovery explored balance recovery mechanisms. The findings showed that balance impairments are most responsive to intervention within the first six months after stroke, corresponding with a heightened period of neuroplasticity. The study highlighted the importance of early, structured, and task-specific rehabilitation during this critical phase, supporting the potential application of the Motor Relearning Program (MRP).

A pilot study published in 2021 evaluated the feasibility of delivering task-specific therapy through telerehabilitation using video conferencing. The intervention included functional training exercises for 25 stroke patients aged 45-70 years over six weeks. Significant improvements were observed in trunk control, sit-to-stand transfers, and walking ability, with positive participant feedback and no reported adverse events. The findings suggest that telerehabilitation can effectively deliver neurophysiological principles such as motor learning.

A clinical trial conducted in 2020 involving 40 subacute stroke patients assessed the effectiveness of task-specific training based on the Motor Relearning Program (MRP). Participants performed repetitive, goal-oriented functional tasks, including transfers and walking. After four weeks, the intervention group demonstrated significant improvements in trunk control and balance compared with the group receiving standard physiotherapy, indicating that MRP is highly effective in improving motor control and coordination when delivered in person.

A systematic review published in 2020 examined 22 randomized trials investigating telerehabilitation interventions for stroke recovery. The findings indicated that telerehabilitation was non-inferior to conventional in-clinic therapy in improving gait, balance, and upper limb function. The review further emphasized that structured and patient-specific telerehabilitation is particularly beneficial during the subacute stage when recovery potential is highest.

A controlled trial published in 2017 assessed the effectiveness of telerehabilitation in improving motor function after stroke. Fifty stroke patients aged 40-70 years were randomly assigned to either a telerehabilitation group or a conventional therapy group. After eight weeks, both groups showed significant improvements in motor function, while the telerehabilitation group achieved superior balance outcomes, demonstrating the effectiveness of remotely delivered motor-focused interventions.

A foundational publication in 2015 described the theoretical framework of the Motor Relearning Program (MRP). The program emphasizes active participation, task analysis, and repetitive practice to retrain functional movements. Based on principles of motor control and neuroplasticity, MRP is considered particularly effective for post-stroke patients during the recovery period of 3-12 months. Although widely accepted for face-to-face rehabilitation, its application through digital platforms remains underexplored.

Another meta-analysis published in 2015 evaluated telerehabilitation programs for stroke patients and concluded that while telerehabilitation improves overall function, many interventions lacked specificity and did not incorporate evidence-based motor learning principles. The findings highlighted the need to strengthen telerehabilitation frameworks through structured approaches such as the Motor Relearning Program.

Despite the increasing adoption of telerehabilitation in post-stroke care, notable gaps remain in the current body of research. No study to date has directly compared conventional telerehabilitation programs, which are typically based on general physiotherapy principles, with telerehabilitation approaches specifically structured around the Motor Relearning Program. While existing evidence supports the use of general telerehabilitation in improving motor function, balance, and participation among stroke survivors, these programs often lack the task-specific, neuroplasticity-driven framework that defines the Motor Relearning Program. Separately, MRP-based interventions delivered in clinical settings have demonstrated superior outcomes in balance, functional mobility, and motor recovery compared to routine therapy. However, a head-to-head comparison between conventional telerehabilitation and MRP-based telerehabilitation has not yet been explored in published literature. Furthermore, most existing studies are limited by small, homogenous sample sizes, non-standardized outcome measures, and the absence of long-term follow-up. The integration of advanced technologies such as wearable sensors and real-time feedback into telerehabilitation protocols also remains underdeveloped. These gaps highlight the urgent need for rigorous, comparative, and technology-integrated research to evaluate the effectiveness of structured, MRP-based telerehabilitation in diverse stroke populations.

Вмешательства

  • Другое Telerehabilitation Based Motor Relearning Program
    Participants will receive a Motor Relearning Program (MRP) delivered through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, task-specific functional training, and cool-down. Exercises include sitting and standing balance training, trunk control, sit-to-stand practice, upper limb reaching, trunk rotation, weight-shifting, step tra
  • Другое Conventional physical therapy
    Participants will receive conventional physiotherapy through secure video conferencing under the supervision of a physiotherapist. The intervention will be provided 3 sessions per week for 6 weeks (18 sessions total). Each session will last 45-60 minutes, including a warm-up, exercise session, and cool-down. The program consists of active-assisted and active range-of-motion exercises, stretching, breathing exercises, strengthening exercises, weight-shifting activities, marching in place, gait tr

Первичные конечные точки

  • Fugl-Meyer Assessment (FMA) Motor Function Score [Срок оценки: Baseline and after 6 weeks of intervention]
  • Berg Balance Scale (BBS) Score [Срок оценки: Baseline and after 6 weeks of intervention]
Вторичные конечные точки (1)
  • Timed Up and Go (TUG) Test [Срок оценки: Baseline and after 6 weeks of intervention]

Критерии участия

Inclusion Criteria: \* Adults aged 40-70 years.

  • Male or female participants.
  • Diagnosed with ischemic or hemorrhagic stroke 3-12 months prior to enrollment.
  • Medically stable and cleared to participate in physical rehabilitation.
  • Mini-Mental State Examination (MMSE) score ≥24.
  • Able to understand and follow verbal instructions.
  • Have access to a smartphone, tablet, or computer with a stable internet connection for telerehabilitation sessions.
  • Willing and able to provide written informed consent.

Exclusion Criteria: \* MMSE score <24 or severe cognitive impairment.

  • Presence of other neurological disorders (e.g., Parkinson's disease or multiple sclerosis).
  • Uncontrolled hypertension or recent cardiac event.
  • Severe visual, auditory, or communication impairments that prevent participation.
  • Currently enrolled in another structured rehabilitation program.
  • Any musculoskeletal or medical condition that would interfere with safe participation in the intervention.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Двойное слепое
Основная цель
Лечение

Центры проведения

Пакистан · 1 центр
  • Aziz Fatimah Hospital — Faisalabad

Публикации

  • Winstein CJ, Stein J, Arena R, Bates B, Cherney LR, Cramer SC, Deruyter F, Eng JJ, Fisher B, Harvey RL, Lang CE, MacKay-Lyons M, Ottenbacher KJ, Pugh S, Reeves MJ, Richards LG, Stiers W, Zorowitz RD; American Heart Association Stroke Council, Council on Cardiovascular and Stroke Nursing, Council on Clinical Cardiology, and Council on Quality of Care and Outcomes Research. Guidelines for Adult Stro PMID 27145936
  • Ghrouz A, Marco E, Munoz-Redondo E, Boza R, Ramirez-Fuentes C, Duarte E. The effect of motor relearning on balance, mobility and performance of activities of daily living among post-stroke patients: Study protocol for a randomised controlled trial. Eur Stroke J. 2022 Mar;7(1):76-84. doi: 10.1177/23969873211061027. Epub 2022 Feb 11. PMID 35300258
  • Khallaf ME. Effect of Task-Specific Training on Trunk Control and Balance in Patients with Subacute Stroke. Neurol Res Int. 2020 Nov 17;2020:5090193. doi: 10.1155/2020/5090193. eCollection 2020. PMID 33294224
  • Chen J, Jin W, Zhang XX, Xu W, Liu XN, Ren CC. Telerehabilitation Approaches for Stroke Patients: Systematic Review and Meta-analysis of Randomized Controlled Trials. J Stroke Cerebrovasc Dis. 2015 Dec;24(12):2660-8. doi: 10.1016/j.jstrokecerebrovasdis.2015.09.014. Epub 2015 Oct 23. PMID 26483155
  • Cramer SC, Dodakian L, Le V, See J, Augsburger R, McKenzie A, Zhou RJ, Chiu NL, Heckhausen J, Cassidy JM, Scacchi W, Smith MT, Barrett AM, Knutson J, Edwards D, Putrino D, Agrawal K, Ngo K, Roth EJ, Tirschwell DL, Woodbury ML, Zafonte R, Zhao W, Spilker J, Wolf SL, Broderick JP, Janis S; National Institutes of Health StrokeNet Telerehab Investigators. Efficacy of Home-Based Telerehabilitation vs I PMID 31233135
  • Laver KE, Adey-Wakeling Z, Crotty M, Lannin NA, George S, Sherrington C. Telerehabilitation services for stroke. Cochrane Database Syst Rev. 2020 Jan 31;1(1):CD010255. doi: 10.1002/14651858.CD010255.pub3. PMID 32002991
  • Alwadai B, Lazem H, Almoajil H, Hall AJ, Mansoubi M, Dawes H. Telerehabilitation and Its Impact Following Stroke: An Umbrella Review of Systematic Reviews. J Clin Med. 2024 Dec 26;14(1):50. doi: 10.3390/jcm14010050. PMID 39797132
  • Feigin VL, Brainin M, Norrving B, Martins S, Sacco RL, Hacke W, Fisher M, Pandian J, Lindsay P. World Stroke Organization (WSO): Global Stroke Fact Sheet 2022. Int J Stroke. 2022 Jan;17(1):18-29. doi: 10.1177/17474930211065917. PMID 34986727

Идентификаторы

NCT: NCT07725003 · REC/RCR & AHS/25/0201

Первоисточники (государственные реестры)

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