Ultrasound-Guided Proximal Superior Cluneal Nerve Block for Superior Cluneal Nerve Entrapment

Официальное название

Clinical Outcomes of Ultrasound-Guided Proximal Superior Cluneal Nerve Block in Patients With Superior Cluneal Nerve Entrapment

Обзор

Superior cluneal nerve entrapment (SCNE) is an underrecognized cause of chronic low back pain and gluteal pain that may mimic lumbar spine disorders. Ultrasound-guided proximal superior cluneal nerve block has increasingly been used in routine clinical practice .Diagnostic superior cluneal nerve block is commonly used to confirm the diagnosis, whereas ultrasound-guided proximal superior cluneal nerve block has emerged as a therapeutic option. This prospective observational cohort study aims to evaluate the clinical outcomes of ultrasound-guided proximal superior cluneal nerve block in patients with clinically diagnosed superior cluneal nerve entrapment who undergo the procedure as part of routine clinical care. Pain intensity, disability, and neuropathic pain characteristics will be assessed at baseline and during follow-up to evaluate treatment outcomes.

Подробное описание

Superior cluneal nerve entrapment (SCNE) is an increasingly recognized cause of chronic low back pain that may be overlooked or misdiagnosed as lumbar radiculopathy or other degenerative lumbar disorders. Accurate diagnosis is essential because patients with SCNE may benefit from targeted peripheral nerve interventions rather than treatments directed at the lumbar spine.

Ultrasound-guided proximal superior cluneal nerve block has emerged as a practical technique for both diagnostic confirmation and therapeutic management of SCNE. Compared with landmark-based approaches, ultrasound guidance enables real-time visualization of relevant anatomical structures and standardized needle placement. Despite increasing clinical use, prospective evidence evaluating the clinical outcomes of this technique remains limited.

This prospective observational cohort study will enroll patients with clinically diagnosed superior cluneal nerve entrapment who undergo ultrasound-guided proximal superior cluneal nerve block as part of routine clinical care. Pain intensity, disability, and neuropathic pain characteristics will be evaluated at baseline and at 1- and 3-month follow-up visits using validated clinical outcome measures.

The primary objective is to evaluate changes in pain intensity following ultrasound-guided proximal superior cluneal nerve block. Secondary objectives include evaluating changes in disability and neuropathic pain characteristics after treatment and documenting the clinical outcomes of this intervention during routine practice.

Вмешательства

• Процедура Ultrasound-Guided Proximal Superior Cluneal Nerve Block
  Ultrasound-guided proximal superior cluneal nerve block will be performed as part of routine clinical care in patients with clinically diagnosed superior cluneal nerve entrapment. The proximal superior cluneal nerve will be targeted using a standardized ultrasound-guided interfascial technique. A standardized injectate will be administered according to the study protocol. All procedures will be performed by an experienced pain physician using the same technique for all participants.

Первичные конечные точки

• Change in Pain Intensity [Срок оценки: Baseline, 1 month, and 3 months]

Вторичные конечные точки (3)

• Change in Oswestry Disability Index (ODI) Score [Срок оценки: Baseline, 1 month, and 3 months]
• Douleur Neuropathique 4 (DN4) [Срок оценки: Baseline, 1 month, and 3 months]
• Treatment Response [Срок оценки: 1 month and 3 months]

Критерии участия

Критерии включения

• Age 18-75 years.
• Chronic low back and/or gluteal pain persisting for at least 3 months.
• Localized pain and/or tenderness over the posterior iliac crest.
• At least 50% reduction in pain intensity following diagnostic superior cluneal nerve block.
• Failure of conservative treatment.
• Ability to provide written informed consent.

Критерии исключения

• Previous superior cluneal nerve surgery.
• Active local or systemic infection.
• Bleeding disorders or contraindications to the procedure.
• Allergy to study medications.
• Pregnancy.
• Severe cognitive impairment or inability to complete study assessments.
• Additional interventional pain procedures involving the affected region during follow-up.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

Turkey (Türkiye) · 1 центр

• Gaziosmanpasa Research and Education Hospital — Gaziosmanpaşa

Публикации

• Bodner G, Platzgummer H, Meng S, Brugger PC, Gruber GM, Lieba-Samal D. Successful Identification and Assessment of the Superior Cluneal Nerves with High-Resolution Sonography. Pain Physician. 2016 Mar;19(3):197-202. PMID 27008294
• Luo X, Zhao Y. Ultrasound-Guided Superior Cluneal Nerve Block: A Narrative Review. J Pain Res. 2024 May 22;17:1829-1836. doi: 10.2147/JPR.S462166. eCollection 2024. PMID 38799273
• Nielsen TD, Moriggl B, Barckman J, Jensen JM, Kolsen-Petersen JA, Soballe K, Borglum J, Bendtsen TF. Randomized trial of ultrasound-guided superior cluneal nerve block. Reg Anesth Pain Med. 2019 May 6:rapm-2018-100174. doi: 10.1136/rapm-2018-100174. Online ahead of print. PMID 31061111

Идентификаторы

NCT: NCT07712406 · MEDIPOL-EC-846-2026

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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