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Набор скоро начнётся NCT07701213

Blood Flow Restriction and Aerobic Exercise in Iron Deficiency Anemia

Без фазы С лечением Iron Deficiency Anaemia

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: aerobic exercise + blood flow restriction, aerobic exercise.
Кому может быть актуально
Состояния в реестре: Iron Deficiency Anaemia. Базовые параметры: 19 лет — 25 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Список центров уточняется — проверьте первичный протокол.
Следующий шаг
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Официальное название

Impact of Blood Flow Restriction on Hematological Factors in Anemic Young Females

Обзор

Preventing iron deficiency anemia is essential for strengthening adolescent health and ensuring their full development. Strategies such as improving nutrition, expanding the availability of iron-fortified products, implementing pharmacological prevention, and raising awareness play a crucial role in addressing this issue.

Подробное описание

Anemia is a global public health problem affecting both developing and developed countries at all ages, with major consequences for human health as well as social and economic burden. Iron deficiency affects more than 2 billion people world wide, and iron deficiency anemia (IDA) remains to be the top cause of anemia.

For decades, blood flow restriction (BFR), originating from Japan, has become one of the most popular techniques in physiotherapy. To perform the BFR technique, a controlled tourniquet is performed, generating a gradual mechanical pressure just below it, affecting blood flow (both arterial and venous) and generating a hypoxia in the restricted area. For the realization of the tourniquet, mechanical cuffs are used, which are inflated and regulate the pressure generated in the compression zone, although nylon or elastic cuffs are also used for the realization of the tourniquet.

Вмешательства

  • Устройство aerobic exercise + blood flow restriction
    Twenty five females will be subjected to supervised blood flow restriction combined with aerobic exercise program. participated in 3 months exercise training protocol, which included three walking training sessions per week on a treadmill set at a speed 3 km/h. They experienced 3 session/week and each session include 5-10 minutes .A pressure of between 140 and 200 mmHg was applied using a sphygmomanometer cuff placed at the thigh of the BFR group. The pressure of the cuff was increased until the
  • Процедура aerobic exercise
    participated in 3 months exercise training protocol, which included three walking training sessions per week on a treadmill set at a speed 3 km/h. They experienced 3 session/week and each session include 5-10 minutes warming up and five training sets (each lasting 2 min) with a 1 min rest period between each exercise session and ended with 5-10 minutes cooling down.

Первичные конечные точки

  • haemoglobin concentration [Срок оценки: Baseline and 12 weeks]
  • Serum ferritin level [Срок оценки: Baseline and at 12 weeks]
  • Haematocrit [Срок оценки: Baseline and at 12 weeks]
  • Red blood cell (RBC) count [Срок оценки: baseline and at 12 week]
  • Mean corpuscular volume (MCV) [Срок оценки: baseline and at 12 week]
  • Mean corpuscular haemoglobin (MCH) [Срок оценки: baseline and at 12 week]
Вторичные конечные точки (3)
  • Functional capacity assessed using the Incremental Shuttle Walk Test (ISWT) [Срок оценки: baseline and at 12 week]
  • Quality of life assessed using the SF-36 questionnaire [Срок оценки: baseline and at 12 week]
  • Estimated maximal oxygen consumption (VO₂max) derived from the ISWT [Срок оценки: baseline and at 12 week]

Критерии участия

Критерии включения

  • Hb more than 8 and less than 12 in females.
  • Age: 19-25 year.
  • BMI ranging from 25 to 29.9 kg/m2.
  • No existing inflammatory conditions including rheumatoid arthritis disorders of the lower extremities.
  • Physical activity level less than 150 min per week

Критерии исключения

  • unstable hypertension, venous thromboembolism, hypercoagulable states, varicose veins, pregnancy, and hemophilia.
  • inherited or acquired red cell disorders (haemoglobinopathies).
  • acute or chronic infections (malaria, tuberculosis, HIV),.
  • severe anemia (Hb <8 g/dL).
  • History of cardiovascular diseases.
  • Nutritional anemia (B12/folate)
  • Pregnancy.
  • Peripheral arterial disease.
  • Intermittent claudication.
  • Non smokers

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Открытое
Основная цель
Лечение

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT07701213 · P.T.REC/012/006440 · P.T.REC/012/006440

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗