Preoperative Versus Postoperative Interscalene Block in Arthroscopic Rotator Cuff Repair

Официальное название

Pre-Procedure Versus Post-Procedure Administration of Interscalene Block in Arthroscopic Rotator Cuff Repair: Effects on Early Pain Control and Functional Outcomes

Обзор

This study is evaluating whether the timing of an interscalene nerve block affects pain control and recovery after arthroscopic rotator cuff repair surgery. An interscalene block is commonly used to reduce pain after shoulder surgery. However, it is not known whether administering the block before surgery or after surgery provides better outcomes. Participants undergoing arthroscopic rotator cuff repair are assigned to receive the interscalene block either before the surgical incision or after completion of the procedure. The study compares postoperative pain levels, opioid medication use, length of hospital stay, and ultrasound imaging quality during block administration between the two groups. Functional recovery is also assessed using patient-reported outcome measures during follow-up. The investigators hypothesize that administration of the interscalene block before surgery may provide superior early pain control and reduce postoperative opioid requirements while maintaining similar functional outcomes compared with administration after surgery.

Подробное описание

Postoperative pain remains a major challenge following arthroscopic rotator cuff repair despite advances in multimodal analgesia protocols. Inadequate pain control may delay rehabilitation, increase opioid consumption, prolong hospitalization, and negatively affect patient satisfaction. Ultrasound-guided interscalene block has become a cornerstone of perioperative pain management for shoulder surgery because of its proven analgesic efficacy and favorable safety profile.

Although interscalene block is routinely used in clinical practice, the optimal timing of administration remains controversial. Administration before surgical incision may provide preemptive analgesic effects by attenuating central sensitization and reducing nociceptive input during surgery. In contrast, administration after completion of surgery has been proposed as a strategy to extend the duration of postoperative analgesia. Existing literature provides limited and inconsistent evidence regarding the comparative clinical benefits of these approaches in patients undergoing arthroscopic rotator cuff repair.

This study was designed to evaluate the impact of interscalene block timing within a contemporary shoulder surgery pathway. In addition to its potential influence on perioperative analgesia, the timing of block administration may affect procedural workflow and ultrasound visualization of relevant anatomical structures. Improved understanding of these factors may contribute to optimization of perioperative management strategies and support evidence-based recommendations for regional anesthesia practices in arthroscopic shoulder surgery.

Первичные конечные точки

• Early Postoperative Pain Intensity [Срок оценки: Pre-procedure, postoperative 6th, 12th, 24th hours]

Вторичные конечные точки (6)

• Postoperative Opioid Consumption [Срок оценки: 24 hours after surgery]
• Patient-Controlled Analgesia Usage [Срок оценки: 24 hours after surgery]
• Duration of hospitalization following arthroscopic rotator cuff repair. [Срок оценки: From surgery until hospital discharge]
• Ultrasound Image Quality During Interscalene Block Administration [Срок оценки: At the time of interscalene block administration]
• Oxford Shoulder Score [Срок оценки: Baseline, 3 months, and 6 months after surgery]
• Disabilities of the Arm, Shoulder and Hand (DASH) Score [Срок оценки: Baseline, 3 months, and 6 months after surgery]

Критерии участия

Критерии включения

• Adults aged 18 years or older.
• Patients undergoing primary arthroscopic rotator cuff repair.
• Presence of a repairable small-, medium-, or large-sized rotator cuff tear confirmed by clinical and imaging evaluation.
• Receipt of an ultrasound-guided interscalene nerve block as part of perioperative pain management.
• Ability to provide informed consent and comply with study follow-up requirements.

Критерии исключения

• Irreparable rotator cuff tears.
• Partial-thickness rotator cuff tears not requiring repair.
• Revision rotator cuff repair procedures.
• Concomitant shoulder procedures that could substantially influence postoperative pain or functional outcomes (e.g., shoulder arthroplasty, fracture fixation).
• Previous surgery on the affected shoulder.
• Contraindications to interscalene nerve block, including local anesthetic allergy, infection at the injection site, or severe neurologic disease affecting the brachial plexus.
• Chronic opioid use or opioid dependence before surgery.
• Inability to complete study questionnaires or follow the postoperative rehabilitation protocol.
• Missing baseline or follow-up data required for outcome assessment.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

Turkey (Türkiye) · 1 центр

• Istinye University Bahcesehir Liv Research and Training Hospital — Istanbul

Идентификаторы

NCT: NCT07689448 · ISB-ARCR-2026

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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