The Effect of Lavender Aromatherapy on Cognitive Function in Older Adults With Mild Cognitive Impairment

Обзор

1. To analyze the therapeutic effects of lavender aromatherapy on memory function and overall cognitive function in older adults with Mild Cognitive Impairment (MCI); 2. To analyze whether lavender aromatherapy improves executive function, language ability, attention, visuospatial ability, anxiety, depression, quality of life, and sleep in older adults with MCI.

Подробное описание

The intervention protocol was established as follows: Based on the elderly participant's usual bedtime, the time of going to bed was recorded. The participant was instructed to assume a comfortable sleeping position, use the graduated dropper provided with the essential oil bottle to measure 0.15 ml (approximately 3 drops; theoretically, 0.05 ml per drop) of diluted lavender essential oil, and drip it vertically onto the upper center of a cotton pad. The cotton pad was then pinned to the collar with a safety pin, and the participant was instructed to inhale the scent evenly for 30 minutes. Afterward, the intervention staff or caregiver will remove the cotton pad. The intervention will be conducted 5 days a week for 12 weeks.

Вмешательства

• Другое aromatherapy
  Participants in the intervention group will receive aromatherapy inhalation for 30 minutes per session, five times a week, over a period of 12 week

Первичные конечные точки

• Gobal cognitive function [Срок оценки: Week 12]
• Memory [Срок оценки: Week 12]

Вторичные конечные точки (8)

• Language function [Срок оценки: Week 12]
• Executive function [Срок оценки: Week 12]
• Visual space [Срок оценки: Week 12]
• Attention [Срок оценки: Week 12]
• Anxiety [Срок оценки: Week 12]
• Depression [Срок оценки: Week 12]
• Sleep Quality [Срок оценки: Week 12]
• Quality of Life assess [Срок оценки: Week 12]

Критерии участия

Критерии включения

• The MCI mentioned in this study meets the diagnostic criteria proposed by the \*Chinese Expert Consensus on the Diagnosis and Treatment of Alzheimer's Disease-Derived Mild Cognitive Impairment (2021)\*: cognitive impairment reported by the patient or an informant, or identified by an experienced clinician; objective evidence of impairment in one or more cognitive domains, with episodic memory impairment being the most common; complex instrumental activities of daily living may be mildly impaired, but the ability to perform basic activities of daily living remains independent; the diagnostic criteria for dementia are not met.
• MoCA-Beijing version scores were adjusted for education level: ≤13 for junior high school education or below, ≤19 for high school education, and ≤24 for university education or above; MMSE score >24; ADL score <23.
• Age between 60 and 79 years.
• Normal olfactory function assessed using the "Sniffin' Sticks" test.
• Ability to communicate normally and complete cognitive assessments.
• Residing in a senior care facility with no plans to leave within the next 12 weeks.

Критерии исключения

• Presence of other conditions known to affect cognitive function, such as psychiatric disorders (e.g., schizophrenia, depression).
• History of asthma or any allergic conditions.
• Use of any prescription medications that may impact cognitive function (including psychotropic drugs and others)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Нерандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT07688382 · Lun Shen [2025] No. 237

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗