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Идёт набор NCT07687316

Mental Effort During Low Load Resistance Training in Older Adults

Без фазы С лечением Seniors Old Age Sarcopenia

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Low Intensity Resistance Training with Maximal Mental Effort, Low Intensity Resistance Training.
Кому может быть актуально
Состояния в реестре: Seniors, Old Age, Sarcopenia. Базовые параметры: 65 лет — 85 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
США
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
Официальное название

The Effect of Maximal Mental Effort During Resistance Training on Physical Function and Motor Unit Behavior in Older Adults

Обзор

The goal of this clinical trial is to determine the effect of maximal mental effort combined with low-intensity resistance training on strength and neuromuscular function in older adults. The main questions it aims to answer are: * Does low-intensity resistance training in combination with maximal mental effort increase strength more than low intensity resistance training alone? * Does low-intensity resistance training in combination with maximal mental effort improve neuromuscular function more than low intensity resistance training alone? Participants will be randomly assigned to 1 of 3 groups: * Low intensity resistance training * Low intensity resistance training with maximal mental effort * Control Researchers will compare groups to determine differences in changes in strength, neuromuscular function, and body composition.

Подробное описание

Participants in both training groups will perform 8 weeks of low intensity, whole-body resistance training. Participants in the control group will participate in all testing procedures but not perform any training. Participants from all groups will be instructed to otherwise maintain their normal physical activity levels and dietary habits.

All training sessions will be supervised by research personnel at a Kennesaw State University fitness center. Participants will complete 2 training sessions per week for 8 weeks. Each training session will last about 45-60 minutes and consist of 5 exercises, including both multi-joint (leg press, chest press, back row) and single-joint (knee extension, bicep curl) exercises. Participants will perform 2 sets of 15 repetitions for each exercise for the first 2 weeks, then volume will be increased by progressing to 3 sets for the remaining 6 weeks. There will be a 60-second rest interval between sets and a similar tempo will be used between groups.

Both training groups will perform the same training protocol, but participants in the maximal mental effort group will mentally urge their muscles to contract maximally during each repetition. That is, despite using a low intensity, participants will imagine the feeling of maximal muscle contraction of the primary muscles during each repetition.

Several measures of strength, neuromuscular function, physical function, and body composition will be measured before and after the training or control period.

Вмешательства

  • Поведенческое Low Intensity Resistance Training with Maximal Mental Effort
    This training intervention will be 8 weeks of low intensity resistance training, including whole-body and isolated muscle exercises, where participants will perform maximal mental effort by imagining maximal muscle contraction during each exercise.
  • Поведенческое Low Intensity Resistance Training
    This training intervention will be 8 weeks of low intensity resistance training, including whole-body and isolated muscle exercises.

Первичные конечные точки

  • Change in isokinetic strength of the knee extensors at 60 degrees per second [Срок оценки: Baseline, Week 8]
Вторичные конечные точки (12)
  • Change in isokinetic knee extensor muscle activation as measured by electromyography amplitude [Срок оценки: Baseline, Week 8]
  • Change in isometric knee extensor strength as measured by newton-meters of torque [Срок оценки: Baseline, Week 8]
  • Change in knee extensor muscle activation as measured by electromyography amplitude [Срок оценки: Baseline, Week 8]
  • Change in motor unit firing rate as measured relative to the motor unit recruitment threshold [Срок оценки: Baseline, Week 8]
  • Change in motor unit action potential size as measured relative to the motor unit recruitment threshold [Срок оценки: Baseline, Week 8]
  • Change in handgrip strength as measured in kilograms of force [Срок оценки: Baseline, Week 8]
  • Change in walking speed as measured by time taken to walk 4 meters [Срок оценки: Baseline, Week 8]
  • Change in chair rise performance as measured by number of chair rises performed in 30 seconds [Срок оценки: Baseline, Week 8]
  • Change in bicep curl strength as measured by load lifted in pounds [Срок оценки: Baseline, Week 8]
  • Change in dynamic strength of the lower body muscles during the leg press as measured by load lifted in pounds for 5 repetitions [Срок оценки: Baseline, Week 5, Week 8]
  • Change in muscle composition as measured by ultrasound-derived grey-scale analysis [Срок оценки: Baseline, Week 8]
  • Change in skeletal muscle size as measured by ultrasound-derived cross-sectional area [Срок оценки: Baseline, Week 8]

Критерии участия

Критерии включения

  • Body mass index between 18.5 - 33 kg·m2
  • No structured physical activity in past 2 years
  • Any unstable condition contradicting exercise
  • Independently walk with or without assistive device
  • No significant cognitive impairment

Критерии исключения

  • Score of 22 or lower on Montreal Cognitive Assessment
  • Missing more than 3 training sessions (training groups only)
  • Pacemaker
  • Unstable angina
  • Symptomatic heart failure
  • Uncontrolled arrythmias
  • Uncontrolled hypertension (greater or equal to 160/90)
  • Myocardial infarction in the past 6 months
  • Uncontrolled type 2 diabetes
  • Type 1 diabetes
  • Severe or unstable pulmonary conditions,
  • Currently on supplemental oxygen therapy
  • Severe hearing loss or visual impairment
  • Alzheimer's Disease or significant cognitive impairment
  • Stroke in the past 6 months or ongoing stroke-induced motor impairment
  • Any neurological (e.g., Parkinson's) condition affecting motor control
  • Undergoing chemotherapy
  • Surgery in past 6 months
  • Musculoskeletal injury in the past 6 months
  • Terminal illness
  • Stage 3 or greater chronic kidney disease

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Простое слепое
Основная цель
Другое

Центры проведения

США · 1 центр
  • Kennesaw State University — Kennesaw

Идентификаторы

NCT: NCT07687316 · 2026-Hester

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗