Coherence Breathing Before Cardiopulmonary Exercise Testing

Официальное название

Acute Effects of Coherence Breathing on Cardiopulmonary Exercise Responses in Recreationally Active Adults: A Randomized Crossover Trial

Обзор

This randomized crossover trial will examine the acute effects of pre-exercise coherence breathing on cardiopulmonary exercise responses in recreationally active adults. Participants will complete two experimental conditions in randomized order: 5 minutes of guided coherence breathing and 5 minutes of quiet seated spontaneous breathing. Following each condition, participants will perform a standardized treadmill warm-up and a maximal cardiopulmonary exercise test. Outcomes will include oxygen consumption, heart rate, heart rate recovery, perceived exertion, time to completion, and heart rate variability. The findings may help determine whether coherence breathing can serve as an effective autonomic priming strategy before a bout of maximal exercise

Подробное описание

Slow-paced breathing performed at approximately six breaths per minute has been shown to influence autonomic nervous system activity and heart rate variability. Coherence breathing may improve physiological regulation by enhancing cardiorespiratory synchronization and vagal modulation. However, little is known about whether a brief bout of coherence breathing performed immediately before exercise can influence cardiopulmonary exercise performance. The purpose of this study is to investigate the acute effects of pre-exercise coherence breathing on cardiopulmonary exercise performance and autonomic responses in recreationally active adults. This study will utilize a randomized, counterbalanced crossover design. Recreationally active adults aged 19 to 45 years will complete two experimental conditions in random order separated by a minimum of 48 hours (maximum of 7 days). In one condition, participants will perform 5 minutes of guided coherence breathing using a visual breathing pacer at approximately 6 breaths per minute while seated. In the comparison condition, participants will sit quietly for 5 minutes with spontaneous breathing. Following each condition, participants will complete a standardized treadmill warm-up and a maximal cardiopulmonary exercise test (CPET). Heart rate variability will be assessed during baseline seated rest and during the breathing intervention. Cardiopulmonary variables collected during CPET will include oxygen consumption, heart rate, respiratory responses, and ratings of perceived exertion. Recovery responses over 5 minutes seated include heart rate and blood pressure will also be assessed following exercise.

Findings from this study may improve our understanding of breathing strategies for athletic performance. Specifically, whether slow paced breathing through coherence breathing can serve as a practical autonomic priming strategy before maximal exercise. Moreover, insights from this study may provide insight into the acute interaction between breathing regulation, autonomic function, and exercise responses.

Вмешательства

• Поведенческое Coherence Breathing
  Participants complete 5 minutes of guided coherence breathing which consists or around 6 breathing cycles (5 seconds inhale and 5 seconds exhale)
• Поведенческое Spontaneous Breathing
  Participants sit quietly for 5 minutes with their regular spontaneous breathing

Первичные конечные точки

• Peak Oxygen consumption [Срок оценки: during each maximal exercise test immediately after the breathing condition]

Вторичные конечные точки (4)

• rating of perceived exertion (RPE) [Срок оценки: measured at baseline, during the exercise test and after recovery]
• Heart Rate Recovery [Срок оценки: difference between peak HR during CPET and HR at minute 1, minute 2 and minute 5 of recovery.]
• Time to completion of maximal exercise test [Срок оценки: during the exercise test]
• Peak Heart Rate [Срок оценки: measured during the maximal exercise test]

Критерии участия

Критерии включения

• Adults aged 19 to 45 years.
• Any biological sex.
• Recreationally active, defined as accumulating at least 3 hours per week of moderate-to-vigorous physical activity.
• Able to perform maximal cardiopulmonary exercise testing on a treadmill.
• Able to provide informed consent.
• Cleared for moderate-to-vigorous physical activity based on the PAR-Q+ (or PAR-Q 2023).

Критерии исключения

• Accumulate less than 3 hours per week of moderate-to-vigorous physical activity.
• Presence of a health condition that contraindicates maximal exercise testing, including:

Cardiovascular disease. Pulmonary disease. Metabolic disorders. Neuromuscular disorders. Orthopedic limitations that impair exercise performance.

• Acute illness that would interfere with participation or exercise testing.
• Inability or unwillingness to complete study procedures.
• Inability or unwillingness to provide informed consent.
• Not cleared for moderate-to-vigorous physical activity based on the PAR-Q+ (or PAR-Q+ 2023).

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Перекрёстный дизайн

Маскирование

Простое слепое

Основная цель

Другое

Центры проведения

США · 1 центр

• Monmouth University Graduate Center, Human Performance Lab, Room 222 — West Long Branch

Публикации

• Trinkunas E, Kairiukstiene Z, Trinkunaite M, Poderiene K, Brazdzionyte R, Poderys J. Post-Exercise Controlled Breathing Enhances Cardiovascular Recovery and Autonomic Balance: A Randomised Crossover Study. Medicina (Kaunas). 2026 Feb 3;62(2):318. doi: 10.3390/medicina62020318. PMID 41752717
• Laborde S, Allen MS, Borges U, Dosseville F, Hosang TJ, Iskra M, Mosley E, Salvotti C, Spolverato L, Zammit N, Javelle F. Effects of voluntary slow breathing on heart rate and heart rate variability: A systematic review and a meta-analysis. Neurosci Biobehav Rev. 2022 Jul;138:104711. doi: 10.1016/j.neubiorev.2022.104711. Epub 2022 May 24. PMID 35623448
• Sevoz-Couche C, Laborde S. Heart rate variability and slow-paced breathing:when coherence meets resonance. Neurosci Biobehav Rev. 2022 Apr;135:104576. doi: 10.1016/j.neubiorev.2022.104576. Epub 2022 Feb 12. PMID 35167847

Идентификаторы

NCT: NCT07650279 · SP2645

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗