Набор скоро начнётся NCT07625839

A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid With 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on Active Periodontal Status and Surface Roughness and Biocompatibility

Без фазы С лечением Hyaluronic Acid (HA)

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: commonly used hyaluronic Acid with both procedures 3D Printed Versus Milled CAD CAM Provisional Dental Restorations.
Кому может быть актуально: Состояния в реестре: Hyaluronic Acid (HA). Базовые параметры: 25 лет — 50 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Список центров уточняется — проверьте первичный протокол.
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Официальное название

A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid With 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on Active Periodontal Status and Surface Roughness and Biocompatibility (A Randomized Controlled Clinical Trial)

Обзор

A Comparative Clinical Assessment of Adjunctive Hyaluronic Acid with 3D Printed Versus Milled CAD CAM Provisional Dental Restorations on active Periodontal status and Surface Roughness and biocompatibility (A Randomized Controlled clinical Trial).

Подробное описание

This randomized clinical trial evaluates their effects regarding periodontal assessment, including

1. Clinical attachment loss (CAL) 2. Plaque Index (PI) 3. Gingival Index (GI) 4. Bleeding on probing (BOP) 5. using digital scanner then a profilometer to measure surface roughness

Вмешательства

Процедура commonly used hyaluronic Acid with both procedures 3D Printed Versus Milled CAD CAM Provisional Dental Restorations
* Tooth preparation will be performed following standardized prosthodontic guidelines * 1.5-2 mm occlusal reduction * 1-1.2 mm axial reduction * Chamfer finish line * Digital impressions will be obtained using an intraoral scanner. * CAD/CAM Milled and 3D printed Provisionals will be fabricated * Once the study restorations were finished, the intraoral optical impression was made. While control both procedures will be done but without using hyaluronic acid

Первичные конечные точки

Clinical Attachment Loss (CAL) [Срок оценки: Day 0 - month 3]
bleeding on probing (BOP) [Срок оценки: Day 0 - month 3]
Plaque index (PI) [Срок оценки: Day 0 - month 3]

Вторичные конечные точки (2)

biocompatibility [Срок оценки: Day 0 - month 3]
Surface roughness [Срок оценки: Day 0 - month 3]

Критерии участия

Критерии включения

Systemic healthy patients

Patients aged > 25 years
Patients suffering from stage II periodontitis with grade B were included in this study, according to 2017 world workshop classification of periodontal disease (Papapanou et al. 2017).
Patients with interdental clinical attachment loss (CAL) of 3-4 mm
No history of previous periodontal therapy.
No taken medications known to interfere healing or periodontal tissue health such as anticonvulsants, calcium channel blockers, or immunosuppressant drugs.
No previous periodontal surgery at involved sites.
Good oral hygiene and good compliance with the plaque control instructions following initial therapy.
Neither taken antibiotics within the last three months nor nonsteroidal anti-inflammatory drugs within the last three months
Absence of diseases or conditions that would interfere with wound healing such as diabetes mellitus or coagulation disorders
Absence of oral mucosal inflammatory conditions such as aphthous ulcers or lichen planus.