Effects of Combined Thoracic and Diaphragmatic Breathing on Cognitive and Psycho-Physiological Functions

Официальное название

The Effects of Combined Thoracic Expansion Exercises and Slow Diaphragmatic Breathing on Cognitive Function, Brain Activation, Psychological Status, and Head-Shoulder Posture in Healthy Adults

Обзор

This study aims to investigate the effects of a combined thoracic expansion exercise (TEE) and slow diaphragmatic breathing (SDB) program on cognitive function, brain activation, psychological status, and head-shoulder posture in healthy young adults.

Вмешательства

• Другое thoracic expansion exercises and slow diaphragmatic breathing
  4-week supervised training program, consisting of three 30-minute sessions per week. Thoracic expansion exercises consists of chest wall stretching and mobility drills. Followed by 15 minutes of progressive slow diaphragmatic breathing (4-s inhalation/6-s exhalation).
• Другое Sham Block
  During sham TEE, participants perform comfortable thoracic movements without foam rollers or specific breathing coordination. During sham SDB, they maintain a spontaneous, natural respiratory rhythm in relaxed postures. Crucially, the sham protocol lacks the rhythmic pacing (4:6s), diaphragmatic depth cues, and resistance-based progression required to trigger the neuro-cognitive "respiratory-brain" axis.

Первичные конечные точки

• Change from baseline in Working Memory [Срок оценки: Baseline, Week 5 (post-intervention)]
• Change from baseline in Inhibitory Control [Срок оценки: Baseline, Week 5 (post-intervention)]
• Change from baseline in Mental Set Shifting [Срок оценки: Baseline, Week 5 (post-intervention)]
• Change from baseline in Short-Term Memory [Срок оценки: Baseline, Week 5 (post-intervention)]

Вторичные конечные точки (4)

• Change in Heart Rate Variability (HRV) [Срок оценки: Baseline and Week 5 (post-intervention)]
• Change in Posture Alignment [Срок оценки: Baseline and Week 5 (post-intervention)]
• Change in Psychological status [Срок оценки: Baseline and Week 5 (post-intervention)]
• Change in Brain Activation [Срок оценки: Baseline and Week 5 (post-intervention)]

Критерии участия

Критерии включения

• age between 18 to 30 years with at least a high school education to ensure baseline cognitive task comprehension
• the ability to adhere to verbal instructions
• no regular participation in formal breathing exercise or mindfulness training within the past six months.

Критерии исключения

• a history of musculoskeletal, cardiovascular, or cerebrovascular diseases which may interfere this study
• history of respiratory disease or recent respiratory infection
• diabetes mellitus with neuropathy, peripheral neuropathy, or other neurological disorders
• major surgery within the past six months
• Current or past major psychiatric disorders or cognitive impairment
• use of medications significantly affecting cerebral hemodynamics or autonomic function (e.g., beta-blockers, vasodilators) within the past 2 weeks
• use of psychotropic medications or substances known to alter cerebral blood flow, neural activation, or autonomic regulation (e.g., antidepressants, antipsychotics, anxiolytics, stimulants, or sedative-hypnotics).

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Публикации

• Shaffer F, Ginsberg JP. An Overview of Heart Rate Variability Metrics and Norms. Front Public Health. 2017 Sep 28;5:258. doi: 10.3389/fpubh.2017.00258. eCollection 2017. PMID 29034226
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• Yeung MK, Han YMY. Changes in task performance and frontal cortex activation within and over sessions during the n-back task. Sci Rep. 2023 Feb 27;13(1):3363. doi: 10.1038/s41598-023-30552-9. PMID 36849731
• Bianchini E, Warmerdam E, Romijnders R, Hansen C, Pontieri FE, Maetzler W. Cognitive dual-task cost depends on the complexity of the cognitive task, but not on age and disease. Front Neurol. 2022 Oct 3;13:964207. doi: 10.3389/fneur.2022.964207. eCollection 2022. PMID 36313514
• Khng KH, Lee K. The relationship between Stroop and stop-signal measures of inhibition in adolescents: influences from variations in context and measure estimation. PLoS One. 2014 Jul 3;9(7):e101356. doi: 10.1371/journal.pone.0101356. eCollection 2014. PMID 24992683
• Voss A, Schroeder R, Heitmann A, Peters A, Perz S. Short-term heart rate variability--influence of gender and age in healthy subjects. PLoS One. 2015 Mar 30;10(3):e0118308. doi: 10.1371/journal.pone.0118308. eCollection 2015. PMID 25822720
• Pinti P, Tachtsidis I, Hamilton A, Hirsch J, Aichelburg C, Gilbert S, Burgess PW. The present and future use of functional near-infrared spectroscopy (fNIRS) for cognitive neuroscience. Ann N Y Acad Sci. 2020 Mar;1464(1):5-29. doi: 10.1111/nyas.13948. Epub 2018 Aug 7. PMID 30085354

Идентификаторы

NCT: NCT07620249 · 202603092RIN

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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