Идёт набор NCT07612553

MitrAl Valve Calcium aSsEssmEnt With TrueVue Trans-illumination 3D Rendering.

— Наблюдательное Mitral Annular Calcification Mitral Valve Disease

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: Это наблюдательное исследование: исследуемое лечение участникам по протоколу не назначают.
Кому может быть актуально: Состояния в реестре: Mitral Annular Calcification, Mitral Valve Disease. Базовые параметры: от 18 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Италия
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

MitrAl Valve Calcium aSsEssmEnt With TrueVue Trans-illumination 3D Rendering (MAC SEE).

Обзор

The study of calcifications involving the mitral valve is extremely important for the planning of both surgical and percutaneous procedures. Computed tomography (CT) is the non-invasive imaging modality considered the gold standard for the assessment of mitral valve calcifications, thanks to its high spatial resolution and the strong X-ray attenuation of calcium deposits. Echocardiography has traditionally played a limited role in the evaluation of mitral valve calcifications, particularly with three-dimensional imaging. Three-dimensional transesophageal echocardiographic rendering with TrueVue transillumination (Philips Medical Systems, Eindhoven, NL) can provide additional information on the location and extent of calcium on the mitral valve by allowing the placement of a virtual light source beneath the mitral valve. Specifically, the TrueVue system is an advanced software module integrated into Philips echographic equipment that uses data acquired by the transesophageal probe to generate photorealistic images of the heart. Therefore, the ability to evaluate the position and extent of calcifications through transesophageal echocardiography may represent an important step forward for echocardiographic imaging.

Подробное описание

This is a non-profit, observational, bidirectional (prospective and retrospective), multicenter study aimed at comparing the diagnostic accuracy of the following modalities:

* Contrast-enhanced computed tomography (CT) (gold standard) * Three-dimensional transesophageal echocardiography

Первичные конечные точки

Quantification of Mitral Calcifications [Срок оценки: 06/2026]

Вторичные конечные точки (1)

Semiquantitative assessment of mitral calcifications [Срок оценки: 06/2026]

Критерии участия

Критерии включения

Retrospective Cohort

Have already undergone, between February 2025 and September 2025, a contrast-enhanced CT scan and a transesophageal echocardiogram.
Are ≥ 18 years old.

Prospective Cohort

Are scheduled to undergo a contrast-enhanced CT scan and a three-dimensional transesophageal echocardiogram as part of their routine clinical assessment for their underlying cardiac condition, with or without mitral annular or leaflet calcifications.
Are ≥ 18 years old
who have provided written informed consent to participate in the study

Критерии исключения

Retrospective Cohort

The following patients will be considered not eligible:
Patients younger than 18 years.
Patients whose data are incomplete for the purposes of the planned study assessments
Patients who have explicitly refused the use of their data for research purposes.

Prospective Cohort