AI-GF-GNW on Prolonged Grief Reactions

Официальное название

AI-Assisted Grief-Focused Guided Narrative Writing for Subclinical Prolonged Grief Disorder in Bereaved Chinese Adolescents: A Three-Arm Parallel Randomized Controlled Trial.

Обзор

Prolonged Grief Disorder (PGD) is a severe, disabling condition characterized by intense yearning and difficulty accepting the reality of loss, which significantly impairs the academic and psychosocial functioning of bereaved adolescents. While Grief-Focused Cognitive Behavioral Therapy (GF-CBT) is effective, its high cost and resource-intensive nature limit its accessibility for adolescents in mainland China. Grief-Focused Guided Narrative Writing (GF-GNW) offers a scalable, low-cost alternative that facilitates memory integration. Furthermore, integrating Artificial Intelligence (AI) to provide personalized, structured feedback has the potential to simulate therapist functions and enhance intervention efficacy. However, the specific efficacy of AI-assisted feedback in this context remains empirically unvalidated. This parallel randomized controlled trial aims to examine the effectiveness of AI-assisted GF-GNW (AI-GF-GNW) in treating Chinese adolescents (aged 10-19) with subclinical PGD, compared to a no-feedback NF-GF-GNW group and a free writing group. Primary outcomes include PGD symptom severity, while secondary outcomes assess depression, anxiety, and daily functioning. We hypothesize that both active intervention arms will significantly alleviate PGD and related symptoms compared to the free writing group, and that the AI-GF-GNW group will demonstrate a significantly greater reduction in symptoms and functional impairment than the NF-GF-GNW group.

Вмешательства

• Поведенческое AI-Assisted Grief-Focused Guided Narrative Writing
  Participants will independently complete the intervention writing tasks via the H5 platform. Participants were required to complete a 6-day, 3-session narrative writing task. Each session requires more than 20 minutes of uninterrupted writing. Session 1 requires describing the specific details and feelings of the bereavement event; Session 2 requires describing the negative impact of the event and one's own negative feelings; Session 3 requires a description of the positive impact of the event a
• Поведенческое No-Feedback Guided Narrative Writing
  All processes are the same as the AI-GF-GNW group, except that when participants complete their writing and submit, the platform will only display a "submission successful" prompt and will not provide any feedback on the writing content.
• Поведенческое Free Writing
  Participants in the FWG will not receive structured guidance, and are only required to write freely about their loss experiences. The writing sessions will follow the same schedule and duration as the other groups.

Первичные конечные точки

• Prolonged Grief Disorder-13-Revision (PG-13-R) [Срок оценки: Baseline (0 Day), post-treatment assessment (5 Day), follow-up assessment (35 Day)]
• Patient Health Questionnaire (PHQ-9) [Срок оценки: Baseline (0 Day), post-treatment assessment (5 Day), follow-up assessment (35 Day)]

Вторичные конечные точки (2)

• Generalized Anxiety Disorder (GAD-7) [Срок оценки: Baseline (0 Day), post-treatment assessment (5 Day), follow-up assessment (35 Day)]
• WHO Disability Assessment Schedule-short version(WHODAS 2.0) [Срок оценки: Baseline (0 Day), post-treatment assessment (5 Day), follow-up assessment (35 Day)]

Критерии участия

Критерии включения

• Junior and senior high school students currently studying in Chinese Mainland, aged 10-19;
• Between 6 and 60 months prior to the experimental period, experienced the death of a significant family member or close friend or close friend;
• The total symptom score of PG-13-R is between 20-29 points;
• Ability to write and understand written guidelines, to use the mobile phone to interact with AI;
• Consent to participate in the study.

Критерии исключения

• Diagnosed or previously diagnosed with mental illness
• The bereavement time does not meet the time window
• PG-13-R score is not within the range
• At present, there is suicidal ideation or recent severe self harm behavior (Reynolds' Suicidal Ideation Questionnaire, SIQ-JR-4>0), and a crisis intervention hotline is provided when necessary.
• Has received other grief counseling or is currently taking psychiatric medication within the past month

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Тройное слепое

Основная цель

Лечение

Центры проведения

Китай · 1 центр

• Peking University — Пекин

Идентификаторы

NCT: NCT07589088 · AI-assisted Grief-Focused GNW

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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