Sciatic Neural Mobilization in Lumbar-Related Leg Pain

Официальное название

Immediate Effects of Sciatic Neural Mobilization on Balance and Proprioception in Patients With Low Back Pain and Radiating Leg Pain: A Prospective Randomized Clinical Trial

Обзор

Low back pain is one of the most prevalent musculoskeletal disorders worldwide and significantly reduces individuals' quality of life, functional capacity, and productivity. Lumbar-related leg pain (LRLP) is observed in a substantial proportion of patients with low back pain and is associated with neurodynamic dysfunctions arising from peripheral nerve sensitization. Although the effects of neural mobilization on pain and functional outcomes have been investigated in the literature, studies examining its short-term effects on balance and proprioception remain limited. Therefore, this study aims to determine the immediate effects of sciatic nerve neural mobilization on balance and proprioception in individuals with LRLP exhibiting peripheral nerve sensitivity. The study will be designed as a prospective, randomized, controlled clinical trial. Participants will be recruited from individuals presenting to the Istinye University Health Practice and Research Center Hospital who meet the inclusion criteria. Following random allocation, 52 participants will be assigned either to the intervention group (neural mobilization) or the sham group (sham mobilization). In addition to a single-session standard conventional physiotherapy program, each group will receive its respective intervention protocol. Assessments will be conducted at two time points: before treatment and immediately after treatment. Static and dynamic balance as well as proprioception will be evaluated using the ProKin balance system; muscle mechanical properties will be assessed using the MyotonPRO device; pain threshold will be measured with an algometer; and flexibility will be evaluated using the sit-and-reach test.

Вмешательства

• Другое Sciatic neural mobilization
  Participants in the intervention group will receive sciatic neural mobilization in addition to a single-session standard conventional physiotherapy program. The conventional treatment program will consist of hot pack application, transcutaneous electrical nerve stimulation (TENS), and exercises aimed at improving lumbar muscle activation, flexibility, and proprioceptive awareness. Sciatic neural mobilization will be performed based on controlled neural sliding and tensioning principles along the
• Другое Sham sciatic neural mobilization
  Participants in the sham group will receive the same single-session standard conventional physiotherapy program as the intervention group. In addition, sham sciatic neural mobilization will be applied. In the sham intervention, procedures similar to those used in the intervention group will be performed at a minimal level without producing therapeutic neural tension or sliding effects. This approach is intended to distinguish the specific effects of the intervention from placebo effects. All pro

Первичные конечные точки

• Static Balance [Срок оценки: 30 minute]
• Dynamic Balance [Срок оценки: 30 minute]
• Proprioception [Срок оценки: 30 minute]

Вторичные конечные точки (5)

• Muscle Tone [Срок оценки: 30 minute]
• Muscle Stiffness [Срок оценки: 30 minute]
• Pressure pain threshold [Срок оценки: 30 minute]
• Flexibility [Срок оценки: 30 minute]
• Global Change Scale (GCS) [Срок оценки: 30 minute]

Критерии участия

Критерии включения

• Having low back pain accompanied by radiating leg pain (radicular or pseudoradicular pain) for at least 3 weeks
• Demonstration of peripheral nerve sensitivity through clinical evaluation and neurodynamic tests
• Pain intensity of at least 3 on the Visual Analog Scale (VAS)
• Ability to understand verbal and written Turkish instructions
• Providing signed informed consent

Критерии исключения

• Presence of surgical indication due to acute disc herniation or advanced lumbar disc pathology
• History of spinal surgery or spinal trauma
• Low back pain associated with other pathologies (e.g., rheumatic diseases, multiple sclerosis, malignancy)
• Instability conditions such as spondylolysis and spondylolisthesis
• Pregnancy
• Obesity (BMI ≥ 30 kg/m²)
• Orthopedic problems or chronic diseases that may limit exercise participation
• Physiotherapy or steroid injection treatment within the last 3 months

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Тройное слепое

Основная цель

Лечение

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT07588919 · 20

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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