Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Whole-Body High-Intensity Interval Training (WB-HIIT).
- Кому может быть актуально
- Состояния в реестре: Overweight and/or Obesity. Базовые параметры: 18 лет — 55 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Бельгия
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Effects of a Whole-body High-intensity Interval Training on Cardiorespiratory Fitness, Musculoskeletal Fitness, Body Composition and Blood Parameters in Overweight Subjects
Обзор
This study aims to evaluate the effects of a supervised whole-body high-intensity interval training (WB-HIIT) program on physical fitness and health outcomes in adults with overweight and obesity. WB-HIIT is a practical and time-efficient training modality based on body-weight exercises performed at high intensity with short recovery intervals. It may offer an accessible approach for improving health in individuals with excess body weight. Participants aged 18 to 55 years with a body mass index (BMI) between 25 and 35 kg/m² will take part in a supervised 10-week WB-HIIT program, performed in small groups and led by trained exercise professionals. Before and after the intervention, participants will undergo assessments including DXA-based body composition analysis, fasting blood sampling, muscular strength testing, a Chester step test, a maximal graded treadmill exercise test with gas-exchange analysis to determine VO₂peak, and functional evaluations (chair-stand, arm-curl, and 6-minute walk test). Physical activity and dietary intake will also be recorded. The primary objective of the study is to assess whether WB-HIIT improves cardiorespiratory fitness (VO₂peak) in adults with overweight. Secondary objectives include evaluating changes in muscular strength, body composition, metabolic markers, and functional capacity. The results may help determine whether an equipment-free WB-HIIT program can serve as an effective and accessible training approach for improving health and physical fitness in adults with overweight and obesity.
Подробное описание
This study investigates the physiological, functional, and metabolic effects of a supervised whole-body high-intensity interval training (WB-HIIT) program conducted entirely in person in adults with overweight and obesity.
Overweight and obesity are associated with decreased cardiorespiratory fitness, metabolic impairments, and increased risk of chronic diseases. In contrast, regular physical activity is known to improve cardiorespiratory fitness, metabolic health, body composition, strength, and quality of life. WB-HIIT, which involves body-weight exercises performed at high intensity with controlled recovery intervals, provides a time-efficient, equipment-free training modality that can be adapted for individuals with excess body weight.
A total of 40 adults aged 18 to 55 years with a BMI between 25 and 35 kg/m² will be recruited and allocated to an intervention and control group. In the intervention group, participants will complete a 10-week supervised WB-HIIT program consisting of 2 to 3 sessions per week. Training sessions will include 8 to 12 whole-body exercises targeting major muscle groups, performed in intervals lasting 20 to 60 seconds with recovery periods adjusted according to participant progression. Intensity will be monitored through heart rate and perceived exertion (Borg CR-10 scale), and progression will be achieved by modifying the number of sets, exercise complexity, and work-to-rest ratio.
All participants will undergo comprehensive pre- and post-intervention evaluations. Body composition will be measured using DXA, and anthropometric measurements will include waist circumference and BMI. Cardiometabolic health will be assessed through fasting blood sampling measuring glucose, insulin, HbA1c, lipid profile, hepatic markers, and additional exploratory biomarkers. Cardiorespiratory fitness will be evaluated using a maximal graded treadmill test with gas exchange analysis to determine VO₂peak and the Chester step test. Functional performance will be assessed through the 30-second chair-stand test, arm-curl test, and 6-minute walk test. Muscular strength will be evaluated through 3-repetition maximum (3-RM) testing and fatigue protocols at 60% of 1-RM for the leg-press and bench-press exercises. Physical activity and dietary habits will also be evaluated before and after the intervention.
The primary outcomes of the study are the changes in VO₂peak and muscle strength following the intervention. Secondary outcomes include changes in body composition, metabolic parameters, and functional capacity. Statistical analyses will include repeated-measures ANOVA and between-group comparisons using parametric or non-parametric methods as appropriate.
This study aims to deepen understanding of the effects of supervised WB-HIIT in overweight adults and to identify practical, scalable training methods that can be implemented in community or clinical settings. The findings may guide the development of accessible exercise-based health strategies for improving fitness and metabolic health in this population.
Вмешательства
- Поведенческое Whole-Body High-Intensity Interval Training (WB-HIIT)
A structured WB-HIIT program using body-weight exercises such as squats, lunges, mountain climbers, and similar multi-joint movements. Sessions last 35-50 minutes and include 3 to 4 sets of interval blocks performed at high intensity. The training is supervised by qualified exercise professionals.
Первичные конечные точки
- Peak oxygen consumption (VO₂peak) [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Muscular strength [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
Вторичные конечные точки (12)
- Estimated VO₂max from the Chester Step Test [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Body composition [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Muscular endurance (fatigue tests at 60% 1-RM) [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Functional performance (chair-stand test) [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Upper-body functional performance (arm-curl test) [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Functional capacity (6-minute walk test) [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Blood biomarkers [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Waist circumference [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Physical activity level using the International Physical Activity Questionnaire [Срок оценки: At Baseline]
- Dietary intake (3-day food record) [Срок оценки: The outcome will be assessed once at baseline and once during the week following completion of the whole-body high-intensity interval training intervention.]
- Weight [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
- Height [Срок оценки: The outcome will be assessed once at baseline and within 72 hours after the last session of the whole-body high-intensity interval training intervention.]
Критерии участия
Критерии включения
- Adults aged 18 to 55 years.
- Body mass index (BMI) between 25 and 35 kg/m².
- Able to provide written informed consent.
- Able to safely participate in high-intensity interval training.
- For participants with BMI > 30 kg/m²: medical clearance from their general practitioner.
Критерии исключения
- BMI < 25 or > 35 kg/m².
- Presence of any chronic medical condition other than overweight/obesity.
- Known cardiovascular, metabolic, respiratory, or musculoskeletal disease that contraindicates high-intensity exercise.
- Pregnancy.
- Inability to perform exercise testing or complete the WB-HIIT program.
- Any condition judged by investigators to interfere with participation or data interpretation.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Распределение
- Нерандомизированное
- Модель
- Параллельные группы
- Маскирование
- Открытое
- Основная цель
- Фундаментальное исследование
Центры проведения
Бельгия · 1 центр
- Université libre de Bruxelles (ULB) — Brussels
Публикации
- Scoubeau C, Bonnechere B, Cnop M, Faoro V, Klass M. Effectiveness of Whole-Body High-Intensity Interval Training on Health-Related Fitness: A Systematic Review and Meta-Analysis. Int J Environ Res Public Health. 2022 Aug 3;19(15):9559. doi: 10.3390/ijerph19159559. PMID 35954911
- Scoubeau C, Carpentier J, Baudry S, Faoro V, Klass M. Body composition, cardiorespiratory fitness, and neuromuscular adaptations induced by a home-based whole-body high intensity interval training. J Exerc Sci Fit. 2023 Apr;21(2):226-236. doi: 10.1016/j.jesf.2023.02.004. Epub 2023 Mar 10. PMID 36970125
Идентификаторы
NCT: NCT07582718 · ULB-WBHIIT-OVERWEIGHT-2026-01 · P2022-344