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Идёт набор NCT07581899

Mind Your Heart Intervention for American Indian Women

Без фазы С лечением Cardiovascular Health

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Culturally-adapted intervention to improve cardiovascular health in American Indian women.
Кому может быть актуально
Состояния в реестре: Cardiovascular Health. Базовые параметры: 18 лет — 55 лет · Женщины.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
США
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
Официальное название

MIND Your Heart Study for American Indian Women

Обзор

The goal of this clinical trial is to learn if a culturally-adapted intervention can improve cardiovascular health in American Indian women. The main questions it aims to answer are: * Can this intervention realistically work for American Indian women? * Do American Indian women find the intervention acceptable? * Does the intervention help improve cardiovascular health in American Indian women? Researchers will compare the intervention group to a control group (a group that does not receive the intervention) to see whether the cardiovascular health of the intervention group improves. Participants will: * Attend 3 data collections over 3 months. * Be randomly assigned to either the intervention group or a control group. * (Intervention group participants) attend 8 weekly classes.

Подробное описание

Conduct a 3-month randomized controlled pilot study to examine feasibility, acceptability, and initial efficacy of an 8-week, culturally-adapted intervention in American Indian women at risk for cardiovascular disease on the following outcomes:

Primary cardiovascular health outcomes:

* blood pressure * heart rate variability * inflammatory markers * metabolic function

Secondary outcomes:

* stress * positive psychological well-being * health behaviors (diet, exercise) * self-regulation * self-efficacy

Вмешательства

  • Поведенческое Culturally-adapted intervention to improve cardiovascular health in American Indian women
    A culturally-adapted cardiovascular health promotion intervention delivered for 8-weeks with American Indian women at risk for cardiovascular disease

Первичные конечные точки

  • Change in Blood pressure [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in Heart rate variability (HRV) [Срок оценки: Baseline and Month 3]
  • Change in Hs-CRP [Срок оценки: Baseline and Month 3]
  • Change in Interleukin-6 (IL-6) [Срок оценки: Baseline and Month 3]
  • Change in Hemoglobin A1c [Срок оценки: Baseline and Month 3]
  • Change in Lipid panel [Срок оценки: Baseline and Month 3]
  • Change in body mass index (BMI) [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in body fat percentage [Срок оценки: Baseline, Week 8, and Month 3]
Вторичные конечные точки (12)
  • Change in contextualized stress: burden [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in perceived stress [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in positive psychological well-being [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in positive emotions [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in negative emotions [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in carotenoid concentration [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in physical activity [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in mindfulness self-regulation [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in eating self-efficacy [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in exercise self-efficacy [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in contextualized stress: stress states [Срок оценки: Baseline, Week 8, and Month 3]
  • Change in Super Woman Schema (SWS) [Срок оценки: Baseline, Week 8, and Month 3]

Критерии участия

Критерии включения

  • Women 18-55 years old who self-identify as Lumbee Indian and
  • Have one or more risk factors for cardiovascular disease:
  • overweight/obese, defined as BMI >25 kg/m\^2
  • hypertensive as measured by study staff
  • physical inactivity
  • Willing and able to follow study procedures

Критерии исключения

  • Women currently enrolled in an organized weight-loss or mindfulness program
  • Pregnant women or women planning to become pregnant during the study period
  • Conditions that exclude study enrollment include:
  • heart murmur
  • congenital heart disease
  • family history of sudden death
  • or orthopedic limitations or health conditions precluding exercise

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Открытое
Основная цель
Профилактика

Центры проведения

США · 1 центр
  • UNC Health Primary and Specialty Care at Pembroke — Pembroke

Идентификаторы

NCT: NCT07581899 · 21-1762 · 5R34HL158947-03 · 5R34HL158947-02 · 1R34HL158947-01

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗