Идёт набор NCT07579468

Impact of Physical Activity During Pregnancy on Biological Markers at Birth in Cord Blood (CORDOMOUV)

— Наблюдательное New Born

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: physical activity level during pregnancy.
Кому может быть актуально: Состояния в реестре: New Born. Базовые параметры: 1 Day — 2 Days · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Франция
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

Currently, an interventional protocol for physical activity during pregnancy is underway at the Clermont University Hospital (PREGMOUV study). In addition, we have implemented a protocol for 2 years monitoring of children birthed of this study (NEOMOUV study). Recent data from the scientific literature show that a woman's engagement in regular and appropriate physical activity during her pregnancy presents few dangers while ensuring benefits for the mother-baby dyad. Indeed, physical activity reduces maternal complications such as preeclampsia, gestational diabetes and depression and has many advantages for the child with in particular a reduction in the risk of macrosomia then obesity and diabetes. Neonatal sepsis is a major risk factor for childhood mortality. There is strong negative association between cord blood levels of calprotectin and sepsis risk in human newborns with levels of calprotectin at birth are significantly lower in infants that later experience blood-culture-proven late-onset neonatal sepsis. In adults, plasma calprotectin levels increase following acute exercise. However after 4 weeks trainging plasma calprotectin level decrease. So in response to acute exercise, plasma calprotectin levels increase but in contrast, there is a negative association between basal plasma calprotectin levels and regular physical activity. Therefore, we do not know what impact mother' regular physical activity can have on the level of calprotectin in the cord blood. The objective of this project is to investigate the impact of physical activity during pregnancy on calprotectin value at cord blood.

Вмешательства

Поведенческое physical activity level during pregnancy
Total physical activity time (in MET minutes/week) of pregnant women measured at Trimestry 3 (explanatory variable)

Первичные конечные точки

Calprotectin levels [Срок оценки: at birth]

Вторичные конечные точки (11)

calprotectin level [Срок оценки: at birth]
calprotectin level [Срок оценки: at birth]
calprotectin level [Срок оценки: at birth]
calprotectin level [Срок оценки: at birth]
calprotectin level [Срок оценки: at birth]
transcriptomic [Срок оценки: at birth]
transciptomic [Срок оценки: at birth]
transciptomic [Срок оценки: at birth]
transciptomic [Срок оценки: at birth]
transciptomic [Срок оценки: at birth]
transciptomic [Срок оценки: at birth]

Критерии участия

Критерии включения

Newborns born to mothers who participated in the PregMouv study (which aims to evaluate an intervention allowing women to better adhere to physical activity: program free/face-to-face/videoconference/mixed) and born at the Clermont Ferrand University Hospital.