Additional Effect of Coherent Breathing With Aerobic Exercise on Cardiopulmonary Parameters and Quality of Life in Stage 1 Hypertensive Individuals

Обзор

This study will use a randomized controlled trial to evaluate the added effects of coherent breathing combined with aerobic exercise versus aerobic exercise alone in 40 adults aged 30-65 with stage 1 hypertension. Participants will be randomly assigned to an intervention group (aerobic exercise plus coherent breathing) or a control group (aerobic exercise only) and will undergo a 4-week program with 5 sessions per week. Cardiopulmonary parameters-including blood pressure, heart rate, respiratory rate, and rate pressure product-will be measured, and quality of life will be assessed using the MINICHAL questionnaire at baseline, 2 weeks, and post-intervention. Data will be analyzed using SPSS version 21.0. The study aims to determine whether coherent breathing provides additional benefits, offering a cost-effective, non-pharmacological strategy for hypertension management in low-resource settings.

Подробное описание

Hypertension, also known as high or raised blood pressure, is a condition in which the blood vessels have persistently raised pressure. A normal reading is less than 120 millimeters of mercury over less than 80 millimeters of mercury. Hypertension is a prevalent condition affecting approximately 1.28 billion individuals globally, with a significant burden observed in low- and middle-income countries such as Pakistan. Stage 1 hypertension is defined by a systolic blood pressure (SBP) between 130-139 mmHg or diastolic blood pressure (DBP) between 80-89 mmHg. High blood pressure causes no signs or symptoms, which is why healthcare providers call it a "silent killer." Non-pharmacological interventions, including aerobic exercise and breathing techniques, have shown promise in improving cardiopulmonary function and quality of life.

Coherent breathing is a controlled breathing technique that involves inhaling and exhaling at a steady, slow pace-typically around five to six breaths per minute, with each inhale and exhale lasting about six seconds. This study aims to evaluate the additional effects of coherent breathing techniques when combined with aerobic exercise, compared to aerobic exercise alone. A randomized controlled trial design will be employed. The study will be conducted over a period of 1 year at Foundation University College of Physical Therapy and Fauji Foundation Hospital Rawalpindi. Ethical approval will be obtained from ERC FUMC and IRC, and the trial will be registered with CBRC and the clinical trial registry. Data will be analyzed using SPSS version 21.0.

This study will fill a critical gap in the literature by assessing the additive benefits of coherent breathing in hypertension management. The findings may support cost-effective, non-pharmacological strategies in low-resource settings, contributing to improved public health outcomes

Вмешательства

• Другое Coherent Breathing.
  Coherent breathing technique involve consciously reducing the breathing rate, typically to fewer than 10 breaths per minute, often around 6 breaths per minute. Coherent breathing is performed for 10 minutes. Aerobic Exercises involving brisk walking, warm up, stepper, static cycling, cool down for a period of 30 min.
• Другое Aerobic Exercises
  Aerobic Exercises involving brisk walking, warm up, stepper, static cycling, cool down for a periof of 30 min.

Первичные конечные точки

• Heart Rate (beats per minute) [Срок оценки: 04 weeks]
• Systolic Blood Pressure (mmHg) [Срок оценки: 04 weeks]
• Diastolic Blood Pressure (mmHg) [Срок оценки: 04 weeks]
• Peripheral Oxygen Saturation (SpO₂, %) [Срок оценки: 04 weeks]
• Respiratory Rate (breaths/minute) [Срок оценки: 04 weeks]
• Rate Pressure Product (HR × SBP) [Срок оценки: 04 weeks]

Критерии участия

Критерии включения

• Both male and female genders.
• Adults aged 30-65 years.
• Patients diagnosed with stage 1 hypertension 130-139/80-89mm Hg according to ACC/AHA 2017 guidelines.
• Mild to moderate physical activity level on IPAQ questionnaire.
• Individuals able to understand and follow the instructions.

Критерии исключения

• Diagnosed uncontrolled hypertensive patients.
• Unstable angina, MI, heart failure, advanced CAD patients, COPD, Asthma.
• Severe neurological, musculoskeletal or gynecological conditions which limit participation in the study.
• Recent history of fracture.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Открытое

Основная цель

Лечение

Центры проведения

Пакистан · 1 центр

• Foundation University Islamabad — Islamabad

Идентификаторы

NCT: NCT07573683 · FUCP/CTR/2026/06

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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