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Идёт набор NCT07568951

Impact of Force Control of Hip Abductor Muscles in Healthy Adults and Individuals With Parkinson's Disease

— Наблюдательное Aging Parkinson's Disease (PD)

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Age, Parkinson's disease (PD).
Кому может быть актуально
Состояния в реестре: Aging, Parkinson's Disease (PD). Базовые параметры: 20 лет — 85 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Тайвань
Следующий шаг
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Официальное название

Impact of Force Control of Hip Abductor Muscles on Postural Control in Middle-aged and Older Adults and Individuals With Parkinson's Disease

Обзор

Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations. While previous studies have mainly focused on sagittal plane balance, the contribution of hip abductor muscles remains unclear, especially regarding their force production and control abilities. Therefore, this study aims to investigate hip abductor muscle force production and force control, and to examine whether these factors are associated with postural control, gait, and balance performance in individuals across different ages and those with PD.

Подробное описание

Both aging and Parkinson's disease (PD) negatively affect postural control and increase the risk of falls, with frontal plane balance being particularly challenging for these populations. Previous studies have mainly focused on sagittal plane balance and have identified the important roles of ankle plantar flexors and knee extensors; however, the contribution of hip abductor muscles-key muscles for frontal plane stability-remains unclear, particularly in terms of their force production and control abilities. Therefore, this study aims to investigate hip abductor muscle force production and force control, and to examine whether these factors are associated with postural control, gait, and balance performance in individuals across different ages and those with PD. Healthy young, middle-aged, and older adults will be recruited from the community, and individuals with PD will be recruited from the Department of Neurology. Healthy participants must be in good health, able to walk independently, demonstrate normal cognitive function, and provide informed consent, while those with neurological, cardiovascular, musculoskeletal, or other conditions affecting motor performance will be excluded. For individuals with PD, inclusion criteria will be a clinical diagnosis of idiopathic PD, Hoehn and Yahr stages 1 to 3, stable anti-PD medication use, and the ability to follow instructions and walk at least 10 m. Exclusion criteria will include psychiatric, immune, integumentary, or musculoskeletal disorders, neurological conditions other than PD, lower extremity pain, uncontrolled cardiovascular disease, or inability to provide informed consent. All participants will undergo a one-time assessment, including maximal voluntary isometric contraction, force steadiness, postural control, and gait performance.

Surface electromyography will be used to assess neuromuscular function, postural control will be evaluated using a force plate under multiple standing conditions, and gait parameters will be measured at both comfortable and fast walking speeds. Statistical analyses will be conducted using ANOVA to examine group differences.

Вмешательства

  • Другое Age
    We compare the young, middle-aged, and old groups
  • Другое Parkinson's disease (PD)
    We compare the healthy group and PD group.

Первичные конечные точки

  • Maximal force [Срок оценки: Baseline]
  • Rate of torque development [Срок оценки: Baseline]
  • Force steadiness [Срок оценки: Baseline]
  • Walking speed [Срок оценки: Baseline]
  • Step Length [Срок оценки: Baseline]
  • Cadence [Срок оценки: Baseline]
  • Single Support Time [Срок оценки: Baseline]
  • Double Support Time [Срок оценки: Baseline]
  • Swing Time [Срок оценки: Baseline]
  • Center of Pressure (COP) Velocity in Balance Tasks [Срок оценки: Baseline]

Критерии участия

Healthy people

Критерии включения

  • 20 to 39 years (young), 40 to 59 years (young), and 60-85 years (old)
  • generally in good health
  • able to walk 10 m independently
  • able to follow all instructions

Критерии исключения

  • neurologic, psychiatric, immune, integumentary, and musculoskeletal diseases or disorders which might influence this study
  • any pain over the lower extremities
  • uncontrolled cardiovascular diseases
  • unable to provide informed consent.

PD

Критерии включения

  • clinical diagnosis of idiopathic PD
  • Hoehn and Yahr stages 1 to 3
  • stable anti-PD medications
  • able to walk 10 m independently
  • able to follow all instructions

Критерии исключения

  • psychiatric, immune, integumentary, and musculoskeletal diseases or disorders which might influence this study
  • neurological conditions other than PD
  • any pain over the lower extremities
  • uncontrolled cardiovascular diseases
  • unable to provide informed consent.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Модель наблюдения
Когортное

Центры проведения

Тайвань · 2 центра
  • Chang Gung Memorial Hospital — Taoyuan
  • Chang Gung University — Taoyuan

Идентификаторы

NCT: NCT07568951 · 202202289A3

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗