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Набор скоро начнётся NCT07562776

A Comparative Study of Preoperative Carbohydrate Loading Dose and Fasting on Postoperative Recovery Time in Elective Abdominal Surgery Patients

Без фазы С лечением This Study Mainly Focus on the Eras Protocol Decreasing Time of Npo and Early Discharge From Hospital to Avoid Hospital Acquired Infections

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Patients will be given 400 mL of a carbohydrate-rich clear drink (10% daxtrosewater) approximately 2-3 hours before induction of anesthesia, according to ERAS guidelines., Standard pre operative fasting.
Кому может быть актуально
Состояния в реестре: This Study Mainly Focus on the Eras Protocol Decreasing Time of Npo and Early Discharge From Hospital to Avoid Hospital Acquired Infections. Базовые параметры: 20 лет — 60 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Список центров уточняется — проверьте первичный протокол.
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Title: A Comparative Study of Preoperative Carbohydrate Loading Dose and Fasting on Postoperative Recovery Time in Elective Abdominal Surgery Patients

Обзор

This randomized controlled trial aims to compare the effect of preoperative carbohydrate loading versus standard overnight fasting on postoperative recovery time in patients undergoing elective abdominal surgery. A total of 144 admitted patients will be randomly assigned to either receive a preoperative carbohydrate drink or follow routine fasting protocols. The primary objective is to evaluate differences in postoperative recovery time between the two groups. Secondary outcomes include length of hospital stay, postoperative complications, and patient comfort. The findings of this study may help optimize preoperative fasting guidelines and improve patient recovery outcomes.

Подробное описание

Preoperative fasting has traditionally been practiced to reduce the risk of aspiration during anesthesia; however, prolonged fasting may lead to increased insulin resistance, patient discomfort, and delayed postoperative recovery. Recent evidence suggests that preoperative carbohydrate loading may improve metabolic response and enhance recovery after surgery.

This single-center randomized controlled trial will be conducted on 144 patients admitted for elective abdominal surgery. Eligible participants will be randomly allocated into two groups: the intervention group will receive a standardized preoperative carbohydrate drink within a defined time before surgery, while the control group will follow conventional fasting guidelines.

The primary outcome of the study is postoperative recovery time, assessed using clinically relevant recovery parameters. Secondary outcomes include length of hospital stay, incidence of postoperative complications, and patient-reported comfort measures.

Data will be collected prospectively during hospital stay and analyzed to determine whether preoperative carbohydrate loading provides significant benefits over standard fasting protocols. The results of this study may contribute to improving perioperative care practices and updating fasting guidelines in surgical patients.

Вмешательства

  • Пищевая добавка Patients will be given 400 mL of a carbohydrate-rich clear drink (10% daxtrosewater) approximately 2-3 hours before induction of anesthesia, according to ERAS guidelines.
    Most previous studies have evaluated preoperative carbohydrate loading in mixed surgical populations or in settings outside Pakistan. Limited local data exist specifically for elective abdominal surgery patients in a single-center Pakistani tertiary care hospital setting. Thisstudy focuses on comparing a standardized carbohydrate loading dose with conventional fasting and assessing its direct impact on postoperative recovery time in your local population. surgery patients specifically It uses a
  • Другое Standard pre operative fasting
    Patients in this group will follow the routine preoperative fasting protocol according to hospital and anesthesia guidelines, including overnight fasting from solids and clear liquids before elective abdominal surgery. No preoperative carbohydrate loading will be give

Первичные конечные точки

  • Post operative insuline resistance [Срок оценки: 24 hours after surgery]
Вторичные конечные точки (1)
  • Time to first oral intake [Срок оценки: 24 hours after surgery]

Критерии участия

Критерии включения

  • • Patients aged 20-60
  • ASA I-II classification.
  • Elective open or laparoscopic abdominal surgeries.

Критерии исключения

  • • Diabetes mellitus or impaired fasting glucose.
  • Emergency surgeries.
  • Patients with hepatic or renal dysfunction.
  • Patients on corticosteroids or insulin-sensitizing agents.
  • Pregnant patients.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Открытое
Основная цель
Поддерживающая терапия

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT07562776 · RCT-ERAS-2026-01

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗