Task-Oriented Upper Limb Training With Focal Vibration in Stroke

Официальное название

Effects of Task-Oriented Upper Limb Training With Localized Vibration on Hand Function, Proprioception, and Muscle Tone in Patients With Stroke

Обзор

This study aims to investigate the effects of task-oriented upper limb training combined with focal vibration on hand function, proprioception, and muscle tone in patients with stroke. Participants will be randomly assigned to either an experimental group receiving task-oriented training with concurrent focal vibration or a control group receiving task-oriented training alone. The intervention will be conducted over 6 weeks. Outcome measures will be assessed before and after the intervention.

Подробное описание

Stroke often results in impairments in upper limb function, including reduced motor control, altered muscle tone, and deficits in proprioception. These impairments can significantly limit functional use of the affected limb in daily activities.

Task-oriented training has been widely used in stroke rehabilitation to improve motor function through repetitive and goal-directed tasks. However, recovery may be limited when sensory input is insufficient. Enhancing sensory feedback, particularly proprioceptive input, may facilitate sensorimotor integration and improve functional outcomes.

Focal vibration applied to muscle or tendon has been shown to stimulate muscle spindle afferents, thereby enhancing proprioceptive input to the central nervous system. When applied during active task performance, focal vibration may further augment motor learning and functional recovery.

This study is designed as a randomized controlled trial to investigate the effects of task-oriented upper limb training combined with focal vibration. Participants will be randomly assigned to either an experimental group receiving task-oriented training with concurrent focal vibration applied to wrist extensor muscles or a control group receiving task-oriented training alone.

The intervention will be conducted for 6 weeks. Outcome measures will include upper limb motor function, proprioception, manual dexterity, and muscle tone, assessed before and after the intervention.

The findings of this study may provide evidence for the effectiveness of combining focal vibration with task-oriented training to enhance upper limb recovery in patients with stroke.

Вмешательства

• Процедура ask-oriented upper limb training combined with focal vibration
  Participants in the experimental group will receive task-oriented upper limb training combined with focal vibration applied to the wrist extensor muscles during task performance. The intervention will be administered for 30 minutes per session, 2 times per week, for 6 weeks, and no vibration will be applied during rest periods.
• Процедура Active Comparator: Task-Oriented Upper Limb Training Alone
  Participants in the control group will receive task-oriented upper limb training without the application of focal vibration, with the device attached to the wrist extensor muscles. The intervention will be administered for 30 minutes per session, 2 times per week, for 6 weeks.

Первичные конечные точки

• Fugl-Meyer Assessment for Upper Extremity (FMA-UE) [Срок оценки: Baseline and immediately after 6 weeks of intervention]

Вторичные конечные точки (5)

• Joint Position Sense (JPS) [Срок оценки: Baseline and immediately after 6 weeks of intervention]
• Thumb Localization Test (TLT) [Срок оценки: Baseline and immediately after 6 weeks of intervention]
• Action Research Arm Test (ARAT) [Срок оценки: Baseline and immediately after 6 weeks of intervention]
• Box and Block Test (BBT) [Срок оценки: Baseline and immediately after 6 weeks of intervention]
• Modified Ashworth Scale (MAS) [Срок оценки: Baseline and immediately after 6 weeks of intervention]

Критерии участия

Критерии включения

• Individuals diagnosed with stroke at least 3 months prior
• Individuals with sufficient cognitive function (Mini-Mental State Examination \[MMSE\] score ≥ 24)
• Individuals able to maintain a seated position independently and perform upper limb functional tasks (Trunk Control Test \[TCT\] ≥ 50)
• Individuals with muscle tone of the affected upper limb of Modified Ashworth Scale (MAS) Grade ≤ 2
• Individuals with Fugl-Meyer Assessment-Upper Extremity (FMA-UE) scores between 20 and 50
• Individuals able to grasp and move objects with the affected upper limb and with muscle strength of Manual Muscle Test (MMT) Grade ≥ 3
• Individuals with impaired proprioception in the affected hand (defined as a score < 2 on the wrist or thumb position item of the FMA-UE)

Критерии исключения

• Individuals within 3 months after stroke onset
• Individuals with fractures, severe soft tissue injuries, or contraindications to focal vibration
• Individuals with severe sensory hypersensitivity or complex regional pain syndrome (CRPS)
• Individuals who received treatments affecting upper limb function within the past 3 months (e.g., botulinum toxin injection, surgery, nerve block)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

South Korea · 2 центра

• Cheongdam Hospital — Seoul
• Sahmyook University — Seoul

Идентификаторы

NCT: NCT07558876 · SU-PT-2026-01-018-002

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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