Набор по приглашению NCT07558785

Telemedicine Self-examination of Speech and Memory for Rapid Detection of Cognitive Impairments Using Machine Learning Methods

Без фазы С лечением Mild Cognitive Impairment (MCI) Dementia Mild Cognitive Impairment (MCI) Amnestic Frontotemporal Degeneration (FTD)

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), the Mississippi Aphasia Screening Test, Amnesia Light and Brief Assessment (ALBA), The Picture naming and immediate recall test (PICNIR).
Кому может быть актуально: Состояния в реестре: Mild Cognitive Impairment (MCI), Dementia, Mild Cognitive Impairment (MCI) Amnestic, Frontotemporal Degeneration (FTD). Базовые параметры: от 40 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Чехия
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

Early cognitive disorders diagnosis is becoming increasingly important due to population aging. The most common causes include Alzheimer's disease and frontotemporal dementia. These diseases are also manifested by changes in speech. NLP allows us to identify and classify these changes. The project aims to develop a web application for self-assessment and automated detection of cognitive disorders from speech. The application will have a form of a dialogue system using machine learning methods. The novelty of this approach is the possibility of an efficient self-assessment of a wide spectrum of the Czech population from their homes and an automated evaluation of test results. Early detection can be followed by a more detailed diagnosis and adequate treatment.

Вмешательства

Диагностический тест The Repeatable Battery for the Assessment of Neuropsychological Status (RBANS)
A brief individually administered battery to measure cognitive decline or improvement across five domains in ages 12 to 89 years 11 months.
Диагностический тест the Mississippi Aphasia Screening Test
he Mississippi Aphasia Screening Test (MAST) was developed as a brief, repeatable screening measure for individuals with severely impaired communication/language skills.
Диагностический тест Amnesia Light and Brief Assessment (ALBA)
Very brief test used to measure deficits of more cognitive functions (short-term, episodic, semantic amnesia, sensory and motor aphasia, apraxia, psychomotor speed).
Диагностический тест The Picture naming and immediate recall test (PICNIR)
Very brief test used to measure deficits of more cognitive functions (short-term, episodic, semantic amnesia, sensory and motor aphasia, apraxia, psychomotor speed).
Диагностический тест Geriatric Depression Scale (GDS-15)
The Geriatric Depression Scale (GDS-15), used to screen for depression in adults aged 55 and older, consists of 15 items that assess mental health based on feelings over the past week.
Диагностический тест The Beck Anxiety Inventory (BAI)
A formative assessment and rating scale of anxiety.
Диагностический тест Digitial Diagnostics of Dementia (DDD)
Our experimental screening battery developed for this study.

Первичные конечные точки

The difference in results between groups of patients with cognitive impairment and healthy individuals in individual parts of our experimental neuropsychological battery Diagnostic Test: Digitial Diagnostics of Dementia (DDD) [Срок оценки: Through study completion, an average of 2 years]
Correlation of the results of our experimental battery (DDD) with RBANS [Срок оценки: Through study completion, an average of 2 years]
Correlation of the results of our experimental battery (DDD) with MAST [Срок оценки: Through study completion, an average of 2 years]
Correlation of the results of our experimental battery (DDD) with ALBA [Срок оценки: Through study completion, an average of 2 years]
Correlation of the results of our experimental battery (DDD) with POBAV [Срок оценки: Through study completion, an average of 2 years]

Критерии участия

Inclusion Criteria for the group of healthy participants:

age over 45 years
Czech as the native language
must meet the criteria in a questionnaire with questions focused on a history of brain injury or psychiatric history or medication use
must achieve normal scores on questionnaires assessing mood

Inclusion Criteria for the group of patients:

\- be diagnosed with mild neurocognitive impairment (MCI) or neurocognitive disorder (dementia) according to the international DSM-5 criteria

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет