Идёт набор NCT07552038

Dental Management of Patients With HIV in Pays de la Loire

— Наблюдательное HIV Infection Acquired Immune Deficiency Syndrome Oral Health Care

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: HIV infection status and clinical characteristics.
Кому может быть актуально: Состояния в реестре: HIV Infection, Acquired Immune Deficiency Syndrome, Oral Health Care. Базовые параметры: от 18 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Франция
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Dental Management of Patients Living With HIV: A Retrospective Study Using COREVIH Data in Pays de la Loire

Обзор

Dental care for people living with HIV has evolved with the widespread use of antiretroviral therapy, which has improved life expectancy and disease control. However, uncertainty remains about whether specific adaptations are still needed during dental procedures due to potential biological abnormalities that may increase infectious or bleeding risks. This study aims to evaluate the proportion of patients living with HIV in the Pays de la Loire region who may require adapted dental management based on biological parameters such as immune status, hematological values, and comorbidities. A retrospective descriptive study will be conducted using anonymized data from 5,603 patients followed in the COREVIH Pays de la Loire database. The results are expected to provide objective data to better inform dental practice and reduce unnecessary precautions or stigmatization in the management of patients living with HIV.

Подробное описание

This is a retrospective descriptive observational study using anonymized data from patients living with HIV followed in the Pays de la Loire region. The dataset includes 5,603 individuals whose data were previously collected as part of routine clinical care and recorded in the Nadis medical database by healthcare professionals involved in HIV management.

Data were provided by the COREVIH Pays de la Loire in an anonymized format and include demographic characteristics (age, sex), HIV-related variables (viral load, duration since diagnosis, antiretroviral therapy status), co-infections (sexually transmitted infections and hepatitis B/C), biological parameters (CD4 lymphocyte count, neutrophil count, platelet count, hemoglobin level), and comorbidities (e.g., diabetes, hypertension, renal disease, cardiovascular conditions, depression).

The primary objective is to determine the proportion of patients presenting biological abnormalities that may increase the risk of infectious or hemorrhagic complications during invasive dental procedures.

Data analysis will consist of descriptive statistics, including frequencies and percentages for categorical variables. The study does not involve any intervention, additional data collection, or direct patient contact.

All data are fully anonymized prior to analysis, ensuring that participants cannot be identified. The study complies with applicable data protection regulations and is based on previously collected clinical data.

Вмешательства

Другое HIV infection status and clinical characteristics
Observational assessment of clinical, biological, and comorbidity data in patients living with HIV, including CD4 count, viral load, hematological parameters, and associated conditions, collected from routine care without any intervention.

Первичные конечные точки

Proportion of Patients Requiring Adapted Dental Management [Срок оценки: At time of data extraction (retrospective baseline)]

Вторичные конечные точки (6)

CD4 Cell Count Distribution [Срок оценки: At time of data extraction (retrospective baseline)]
Neutrophil Count Distribution [Срок оценки: At time of data extraction (retrospective baseline)]
Platelet Count Distribution [Срок оценки: At time of data extraction (retrospective baseline)]
Hemoglobin Level Distribution [Срок оценки: At time of data extraction (retrospective baseline)]
Prevalence of Comorbidities [Срок оценки: At time of data extraction (retrospective baseline)]
Viral Load Status [Срок оценки: At time of data extraction (retrospective baseline)]

Критерии участия

Критерии включения

Adult patients aged ≥18 years
Confirmed diagnosis of HIV infection
Followed at participating hospital centers
Available clinical and biological data relevant to dental care management (CD4 count, viral load, blood count)