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Набор скоро начнётся NCT07538297

Biomechanical Muscle Properties and Balance in Children With Spastic Hemiplegia

Наблюдательное Spastic Hemiplegia

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: hemiplegic group, normal group.
Кому может быть актуально
Состояния в реестре: Spastic Hemiplegia. Базовые параметры: 6 лет — 12 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Список центров уточняется — проверьте первичный протокол.
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
Официальное название

Muscle Biomechanical Properties and Postural Control During Static and Dynamic Standing in Children With Spastic Hemiplegia

Обзор

this study will be conducted to investigate the relationship between muscle tone and dynamic stiffness during balance control and postural stability in children with spastic hemiplegia

Подробное описание

Cerebral palsy (CP) is a neurodevelopmental disorder that affects muscle tone, posture and motor skills. It is the most common cause of motor disability in infants and children. It describes a group of permanent disorders resulting from non-progressive injury to the fetal or infant developing brain. Although the disorder itself is non-progressive, the clinical manifestations change over time as the brain matures.Children with hemiplegic CP often have difficulty performing voluntary movements due to decreased muscle strength and abnormal muscle tone. As a result, the child are unable to generate the necessary force to maintain their positions against gravity, leading to abnormal posture and balance. Myotonometers are compact, noninvasive tools that swiftly and efficiently gauge the biomechanical characteristics of soft tissues. In typically developing (TD) children, in children with developmental disabilities, and in individuals affected by stroke, it was found to be reliable.Balance is the capacity to preserve equilibrium against gravity during upright postures by maintaining the COM over the center of the BOS. It involves reacting to internal (voluntary movements) and external disturbing forces rapidly and effectively through different postural mechanisms to recover stability. It can be classified into static (maintaining the BOS with minimum movements), and dynamic (maintaining the BOS during different body movements). A comprehensive examination of muscle tone in UCP children can help us understand its impact on motor function and develop more targeted therapeutic interventions.

This understanding can have important clinical implications for treatment efficacy, rehabilitation strategies, and neurophysiological assessments. Addressing muscle tone abnormalities provides a more complete picture of the motor impairments and guides the development of individualized treatment plans, ultimately improving functional outcomes for children with UCP. Therefore, this study aimed to investigate the biomechanical properties, such as muscle tone and stiffness in the lower limb muscles of children with UCP compared with their TD peers. Additionally, investigators explored the associations between these properties and balance control in children with hemiplegia.

Вмешательства

  • Другое hemiplegic group
    twenty children with mild degree of spasticity ranged from 1 to 1+ according to Modified Ashworth Scale and Their motor function will be at level I and II according to Gross Motor Function Classification System.Their age will range from 6 to 12 years.
  • Другое normal group
    twenty normal children with no history of neurological or musculoskeletal disorders.

Первичные конечные точки

  • oscillatory frequency [Срок оценки: up to one day]
  • Limits of stability [Срок оценки: up to one day]
  • center of pressure [Срок оценки: up to one day]
Вторичные конечные точки (5)
  • muscle dynamic stiffness [Срок оценки: up to one day]
  • The modified clinical test of sensory integration of balance [Срок оценки: up to one day]
  • muscle elasticity [Срок оценки: up to one day]
  • mechanical stree relaxation time [Срок оценки: up to one day]
  • muscle viscoelastic property [Срок оценки: up to one day]

Критерии участия

Критерии включения

  • Their age will range from 6 to 12 years.
  • Mild degree of spasticity ranged from 1 to 1+ according to Modified Ashworth Scale
  • Their motor function will be at level I and II according to Gross Motor Function Classification System GMFCS
  • They will be able to follow instructions during evaluation procedures.
  • Their caregivers are of a good command of the English language.

Критерии исключения

  • Botulinum toxin injections in the last 6 months.
  • The presence of visual or auditory impairments.
  • Surgical interference in upper, lower limbs and/or spine.
  • Muscloskeletal problems or fixed deformities in the spine and/or upper or/and lower extremities.
  • Seizures.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Модель наблюдения
Другое

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT07538297 · P.T.REC/012/006025

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗