Clinical and Radiographic Evaluation of Ridge Splitting With Simultaneous Implant Placement Covered With Concentrated Growth Factor Membranes in Narrow Alveolar Ridge

Официальное название

Clinical and Radiographic Evaluation of Ridge Splitting With Simultaneous Implant Placement Covered With Concentrated Growth Factor Membranes in Narrow Alveolar Ridge (Case Series).

Обзор

This study aims to evaluate the tissue biotype and bone density around dental implants in patients with narrow alveolar ridge. Ridge splitting with simultaneous implant placement covered with concentrated growth factor (CGF) membranes will be performed. Clinical and radiographic evaluation will be done using periodontal probe and CBCT. Pain will also be assessed using visual analogue scale (VAS) during follow-up period.

Подробное описание

This study is a case series conducted at the outpatient clinic of the Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Cairo University. It aims to evaluate the tissue biotype and bone density around dental implants in adult patients with narrow alveolar ridge.

Alveolar ridge resorption and soft tissue shrinkage after tooth extraction represent a major problem affecting both aesthetics and function. Therefore, preserving alveolar bone and improving soft tissue conditions are essential for successful implant placement. The use of concentrated growth factor (CGF) membranes combined with ridge splitting and simultaneous implant placement may enhance healing, reduce postoperative pain, and improve tissue biotype and bone density.

All patients will undergo clinical and radiographic assessment before the procedure. Preoperative CBCT will be used for surgical planning. Tissue thickness will be measured using a periodontal probe. During surgery, ridge splitting will be performed followed by implant placement, and CGF membranes will be applied over the grafted area. Autologous bone chips will be used for augmentation.

Postoperative evaluation will include assessment of tissue biotype, bone density using CBCT, and pain using visual analogue scale (VAS). Follow-up will be carried out immediately after surgery and up to 4 months postoperatively.

Вмешательства

• Процедура Ridge splitting
  Patients with narrow alveolar ridge will undergo ridge splitting procedure using chisel to allow implant placement.
• Процедура Dental implant placement
  Intervention Description: Dental implants will be inserted simultaneously after ridge splitting in the prepared alveolar ridge.
• Биопрепарат Concentrated Growth Factor (CGF)
  CGF membranes will be prepared from patient venous blood and placed over the grafted area to enhance healing and tissue regeneration.

Первичные конечные точки

• Pain (VAS score) [Срок оценки: 1st day and 3rd day postoperative]

Вторичные конечные точки (1)

• Tissue biotype thickness [Срок оценки: Immediately postoperative and after 4 months]

Критерии участия

Критерии включения

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Patients with narrow alveolar ridge indicated for implant placement Age between 20 and 50 years Good general health Patients with adequate oral hygiene

Критерии исключения

• Patients with systemic diseases affecting bone healing Smokers Pregnant or lactating females Patients with poor oral hygiene Patients with history of radiation therapy in the head and neck region

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Не применимо

Модель

Одна группа

Маскирование

Открытое

Основная цель

Лечение

Центры проведения

Египет · 2 центра

• Cairo university — Cairo
• Faculty of Dentistry, Cairo University — Cairo

Идентификаторы

NCT: NCT07534787 · Omfs 3-3-18.

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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