Investigation on Suicide Risk Factors of Patients With Mood Disorders

Официальное название

Investigation on Suicide Risk Factors of Patients With Mood Disorders in China

Обзор

This study investigates the level and distribution of suicide risk and learned suicide ability of patients with mood disorders, investigates the related risk factors of suicide and suicide ability formation of patients with mood disorders from multiple dimensions (biological, psychological, social and clinical perspectives) and clarifies their importance, forms a list of suicide risk factors, and establishes a prediction model of learned suicide ability formation. Upon enrollment, participants will undergo comprehensive assessments including blood and urine sample collection and scale evaluation. The collection of scientific blood and urine is mainly used for the exploration of molecular mechanism of disease occurrence and development, the discovery and verification of biomarkers. Scale evaluation includes: Beck Scale for Suicide Ideation , Columbia Suicide Severity Rating Scale,, Hamilton Depression Rating Scale , Hamilton Anxiety Rating Scale, PHQ-9, GAD-7, Personal and Social Function Scale , Schihan Disability Scale , Emotional Adjustment Difficulty Scale , Acquired Capability for Suicide Scale, Interpersonal Needs Questionnaire , Ottawa Self-Injury Scale, Chinese version of Stress Perception Scale and Beck Hopelessness Scale . Follow-up was carried out for 3 months, including whether suicide/self-injury occurred, current status, and some baseline questionnaires (such as BSI-CV, GAD-7, PHQ-9, HAMD-17,HAMA, etc.).

Первичные конечные точки

• Columbia Suicide Severity Rating Scale [Срок оценки: baseline, 3 months]

Вторичные конечные точки (8)

• Beck Scale for Suicide Ideation [Срок оценки: baseline, 3 months]
• Hamilton Depression Rating Scale [Срок оценки: baseline, 3 months]
• Hamilton Anxiety Rating Scale [Срок оценки: baseline, 3 months]
• Patient Health Questionnare [Срок оценки: baseline, 3 months]
• Generalized Anxiety Disorder [Срок оценки: baseline, 3 months]
• acquired capability for suicide scale [Срок оценки: baseline, 3 months]
• Interpersonal Needs Questionnaire [Срок оценки: baseline, 3 months]
• Beck Hopelessness Scale [Срок оценки: baseline, 3 months]

Критерии участия

Критерии включения

• Age: 16 to 60 years old;
• seeing a doctor in a psychiatric clinic or a general hospital;
• Willing to cooperate in this research project;
• Sign the informed consent form (minors also need to obtain the informed consent signature of the guardian);
• Meet the diagnostic criteria of ICD-11 mood disorder.

Критерии исключения

• unable to understand the contents of the questionnaire;
• Serious organic diseases such as cardiovascular disease, brain disease, liver disease and kidney disease, and weak body, which affect the respondents of the questionnaire;
• Other circumstances that make it impossible or unwilling to cooperate with the completion of the questionnaire.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

Китай · 1 центр

• Tianjin Anding Hospital — Тяньцзинь

Идентификаторы

NCT: NCT07523490 · MD-SU

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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