Меню
Набор скоро начнётся NCT07521540

Integrated Rehabilitation in HDU for Post-Intensive Care SyndromeLiberation in Patients With PICS

Без фазы С лечением Post-Intensive Care Syndrome (PICS) Critical Illness Recovery Mechanical Ventilation

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Integrated Multidisciplinary Rehabilitation.
Кому может быть актуально
Состояния в реестре: Post-Intensive Care Syndrome (PICS), Critical Illness Recovery, Mechanical Ventilation. Базовые параметры: от 18 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Китай
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Официальное название

Effect of Integrated Multidisciplinary Rehabilitation in a High-Dependency Unit on Outcomes of Patients With Post-Intensive Care Syndrome: A Prospective Interventional Study

Обзор

Post-intensive care syndrome (PICS) is characterized by persistent physical, cognitive, and psychological impairments among survivors of critical illness. Although advances in intensive care medicine have reduced mortality, a large proportion of ICU survivors experience long-term functional impairments after discharge. High-dependency units (HDUs) serve as transitional care settings between intensive care units and general wards. Many critically ill survivors who cannot directly return home are transferred to HDU for continued treatment and rehabilitation. However, evidence regarding systematic multidisciplinary rehabilitation interventions in HDU settings remains limited. This prospective single-center interventional study aims to evaluate the effects of an integrated multidisciplinary rehabilitation model implemented in the HDU on physical, cognitive, and psychological outcomes among patients with post-intensive care syndrome. All enrolled patients will receive standardized integrated medical, nursing, and rehabilitation interventions. Multidimensional functional assessments will be conducted at baseline, during hospitalization, and before discharge from the HDU.

Подробное описание

Post-intensive care syndrome (PICS) includes physical weakness, cognitive impairment, and psychological disorders that occur after critical illness. Previous studies have shown that 50-70% of ICU survivors develop at least one PICS-related impairment within 6-12 months after discharge.

Current interventions mainly focus on ICU-based strategies such as the ABCDEF bundle, which can improve short-term outcomes but may not adequately address long-term functional recovery. Many patients remain severely debilitated after ICU discharge and require transitional care.

The high-dependency unit (HDU) represents a potential critical window for early rehabilitation intervention. Patients in this stage often have multiple functional impairments but remain medically stable enough to participate in rehabilitation programs.

This study will enroll patients transferred from ICU to HDU who meet diagnostic criteria for PICS. Participants will receive an integrated multidisciplinary intervention including medical management, respiratory rehabilitation, physical rehabilitation, nursing care, and cognitive-psychological support.

Functional assessments will be conducted at baseline, every two weeks during hospitalization, and prior to HDU discharge. The study will evaluate changes in physical, cognitive, and psychological outcomes associated with this intervention.

Вмешательства

  • Поведенческое Integrated Multidisciplinary Rehabilitation
    Participants will receive a standardized multidisciplinary rehabilitation program implemented in the HDU, including: Medical management Continuous treatment of primary diseases, medication optimization, complication prevention, and gradual removal of medical devices. Respiratory rehabilitation Respiratory muscle training, airway clearance techniques, and breathing pattern training. Physical rehabilitation Progressive mobilization according to patient tolerance, including passive exercises, ac

Первичные конечные точки

  • Change in Physical Function (CPAx Score) [Срок оценки: Baseline (within 48 hours after HDU admission) and at HDU discharge，assessed up to 2 days]

Критерии участия

Критерии включения

  • Age ≥18 years
  • Diagnosed with post-intensive care syndrome
  • Transferred from ICU to HDU
  • Available paired admission and discharge data

Критерии исключения

  • Death within 24 hours after HDU admission
  • Missing primary outcome data

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение
Не применимо
Модель
Одна группа
Маскирование
Открытое
Основная цель
Лечение

Центры проведения

Китай · 1 центр
  • Beijing Rehabilitation Hospital Affiliated to Capital Medical University — Пекин

Идентификаторы

NCT: NCT07521540 · 2026bkky-hxk-PICS

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗