A Clinical Study on the Effect of Cardiopulmonary Function and Quality of Life in Patients With Acute Coronary Syndrome Complicated by Heart Failure by "Lying-Sitting-Standing" Sequential Baduanjin

Обзор

This study investigates the effects of a sequential "lying-sitting-standing" Baduanjin intervention on patients with acute coronary syndrome complicated by heart failure. By evaluating cardiopulmonary function and quality of life through indicators such as echocardiography, NT-proBNP, 6MWT, NYHA classification, and SF-36, we aim to compare its efficacy with conventional treatment. The objective is to provide new insights for early cardiac rehabilitation strategies in patients with acute coronary syndrome complicated by heart failure

Вмешательства

• Поведенческое standard treatment and routine rehabilitation nursing guidance
  standard treatment and routine rehabilitation nursing guidance
• Поведенческое "Lying-Sitting-Standing" Sequential Baduanjin
  "Lying-Sitting-Standing" Sequential Baduanjin

Первичные конечные точки

• Patients were stratified based on their 6-minute walk test distance [Срок оценки: From enrollment to the end of the 12-week treatment]
• NYHA（New York Heart Association）classification of cardiac function [Срок оценки: From enrollment to the end of the 12-week treatment]
• Left ventricular ejection fraction (LVEF) on echocardiography [Срок оценки: From enrollment to the end of the 12-week treatment]
• C-reactive protein levels [Срок оценки: From enrollment to the end of the 12-week treatment]
• ＳＦ-３６（ShortForm36HealthSurvey） [Срок оценки: From enrollment to the end of the 12-week treatment]
• NT-proBNP（N-terminal pro-B-type natriuretic peptide）levels [Срок оценки: From enrollment to the end of the 12-week treatment]
• FMD（flow-mediated vasodilation） [Срок оценки: From enrollment to the end of the 12-week treatment]
• ADL（Activities of Daily Living Scale） [Срок оценки: From enrollment to the end of the 12-week treatment]

Критерии участия

Критерии включения

• Patients meeting the diagnostic criteria for ACS (including unstable angina, non-ST-segment elevation myocardial infarction, and ST-segment elevation myocardial infarction)
• Complicated by heart failure during hospitalization
• Age ≤ 85 years
• Muscle strength ≥ grade 3
• No history of mental illness, conscious and able to cooperate independently with this study
• Voluntarily participate in this study and sign the informed consent form

Критерии исключения

• Patients with persistent heart failure symptoms or NYHA functional class IV despite optimal pharmacological therapy;
• Patients with contraindications to cardiac rehabilitation, such as uncontrolled hypertension, uncontrolled arrhythmias, or hemodynamic instability;
• Patients with untreated structural heart disease, such as heart failure caused by valvular heart disease or congenital heart disease;
• Patients in the acute phase of various diseases, such as severe infection, deep vein thrombosis, or severe hepatic or renal failure;
• Patients with disabilities, bone or joint diseases, or neurological disorders that preclude participation in Baduanjin exercises;
• Patients with a life expectancy of less than one year;
• Patients currently participating in other clinical trials.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Двойное слепое

Основная цель

Лечение

Центры проведения

Китай · 1 центр

• Second Hospital of Shanxi Medical — Taiyuan

Идентификаторы

NCT: NCT07486791 · SecondShanxiMU01

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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