Virtual Reality Intervention to Reduce Pain in Women Undergoing Elective Oocyte Cryopreservation

This study is a prospective, randomized controlled clinical trial evaluating the effectiveness of virtual reality (VR) in reducing pain among women undergoing elective oocyte cryopreservation.

Eligible participants awaiting oocyte retrieval are recruited at the fertility unit. All participants receive detailed information about the study and provide written informed consent prior to enrollment.

Participants are randomized into two parallel groups. The intervention group receives routine care in addition to exposure to relaxing virtual reality nature scenery using a VR headset for approximately 20 minutes prior to oocyte retrieval. The control group receives routine care without exposure to virtual reality.

Baseline assessments include demographic data, medical history, pain sensitivity questionnaire (PSQ), baseline visual analog scale (VAS) pain score, pain threshold assessment, and vital signs.

Following the procedure, pain is reassessed using the visual analog scale. Analgesic administration is documented from medical records. Additional post-procedure assessments include pain-related parameters and vital signs.

The primary outcome is post-procedure pain intensity measured using the VAS. Secondary outcomes include pain sensitivity measures, analgesic consumption, and physiological parameters.

All collected data include demographic variables, clinical parameters, baseline and post-procedure pain scores, pain-related measures, vital signs, and medication use. Data are coded and stored in a secure institutional database.

Statistical analysis compares outcomes between groups using appropriate parametric or non-parametric methods according to data distribution.

This study aims to assess whether pre-procedure virtual reality exposure can serve as a safe and effective non-pharmacological adjunct for pain reduction in women undergoing elective oocyte cryopreservation.

• Baseline pain sensitivity [Срок оценки: Before oocyte retrieval]
• Heart rate during oocyte retrieval [Срок оценки: Before, during, and after oocyte retrieval and prior to discharge on the day of the procedure]
• Pain intensity prior to discharge [Срок оценки: Prior to discharge (same day as oocyte retrieval)]
• Change in pain intensity from pre-procedure to post-procedure [Срок оценки: From pre-procedure (at admission) to immediately post-procedure in the recovery room]
• Post-procedure analgesic consumption [Срок оценки: From completion of oocyte retrieval until discharge from the recovery unit]
• Systolic blood pressure during oocyte retrieval [Срок оценки: Before, during, and after oocyte retrieval and prior to discharge on the day of the procedure]
• Diastolic blood pressure during oocyte retrieval [Срок оценки: Before, during, and after oocyte retrieval and prior to discharge on the day of the procedure]