Long-term Clinical Outcomes After Retinal Artery Occlusion
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: retinal artery occlusion.
- Кому может быть актуально
- Состояния в реестре: Retinal Artery Occlusion. Базовые параметры: Без ограничений · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- South Korea
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
Не всё понятно в терминах? Прочитайте наш гид для пациентов →
Официальное название
Long-Term Cardiovascular and Cerebrovascular Outcomes After Retinal Artery Occlusion: A Nationwide Study
Обзор
Retinal artery occlusion (RAO) is a rare but vision-threatening vascular disorder that is commonly caused by embolic events originating from the heart or carotid arteries. Patients with RAO are known to have an increased risk of subsequent cardiovascular and cerebrovascular events, including ischemic stroke and myocardial infarction. However, long-term outcomes and optimal medical treatment strategies for these patients remain insufficiently characterized. The purpose of this nationwide population-based study is to investigate the incidence of long-term cardiovascular and cerebrovascular outcomes in patients diagnosed with retinal artery occlusion using the Korean National Health Insurance Service (NHIS) database. In addition, the study aims to evaluate the impact of various medical therapies, including antiplatelet agents, anticoagulants, and statins, on long-term clinical outcomes.
Подробное описание
Retinal artery occlusion (RAO) is an acute retinal vascular disease that results in sudden and severe vision loss. RAO is typically classified into central retinal artery occlusion (CRAO) and branch retinal artery occlusion (BRAO), depending on the site of arterial obstruction. CRAO generally has a worse clinical prognosis compared with BRAO.
Previous studies have demonstrated that RAO is associated with systemic vascular diseases and an increased risk of ischemic stroke and other cardiovascular events. Despite its clinical significance, effective evidence-based treatment strategies for RAO remain unclear.
This study aims to evaluate the epidemiology and long-term cardiovascular outcomes of patients with RAO in Korea using the National Health Insurance Service (NHIS) database, which covers nearly the entire Korean population. Patients newly diagnosed with RAO between January 2010 and December 2024 will be identified.
This nationwide population-based study may help clarify the long-term prognosis of RAO and identify optimal medical treatment strategies for improving clinical outcomes in these patients.
Вмешательства
- Другое retinal artery occlusion
treatment for retinal artery occlusion
Первичные конечные точки
- Occurrence of MACCE [Срок оценки: up to 5 years]
Вторичные конечные точки (8)
- Occurrence of all-cause death [Срок оценки: up to 5 years]
- Occurrence of cardiac death [Срок оценки: up to 5 years]
- Occurrence of myocardial infarction [Срок оценки: up to 5 years]
- Occurrence of revascularization [Срок оценки: up to 5 years]
- Occurrence of stroke [Срок оценки: up to 5 years]
- Occurrence of admission due to heart failure [Срок оценки: up to 5 years]
- Occurrence of atrial fibrillation [Срок оценки: up to 5 years]
- Occurrence of major and clinically relevant non-major bleeding [Срок оценки: up to 5 years]
Критерии участия
Критерии включения
- Patients newly diagnosed with retinal artery occlusion
Критерии исключения
- Patients with a prior diagnosis of retinal artery occlusion before the study period.
- Patients diagnosed with giant cell arteritis.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
South Korea · 1 центр
- Chonnam National University Hospital — Gwangju
Идентификаторы
NCT: NCT07482228 · CNUH-EXP-2026-013