Influence of Individual Traits on Adaptation Processes in Individuals With Alcohol Use Disorder

Обзор

Alcohol Use Disorder (AUD) is a chronic condition that affects behavior, decision-making, and the ability to adapt to changing situations. While many studies have examined AUD from medical and social perspectives, less is known about how individual psychological traits influence the way people with AUD respond to uncertainty and adapt their behavior. This study aims to better understand how personal characteristics such as anxiety, self-esteem, sensitivity to reward and punishment, perfectionism, and cognitive abilities may influence adaptation processes in individuals with AUD. Participants receiving usual care at Paul Brousse Hospital will be invited to take part in a single experimental session lasting about 45 minutes. During this session, they will complete: * A computerized learning task in which they respond to visual stimuli and receive feedback on their performance * Standardized questionnaires assessing psychological traits and cognitive functioning The learning task is designed to evaluate how participants adjust their behavior when the rules of the task change unexpectedly. Researchers will measure how performance changes in response to uncertainty and examine how these changes relate to individual psychological characteristics. This research does not modify participants' medical care and involves no medication or invasive procedures. By improving understanding of the cognitive and behavioral mechanisms involved in Alcohol Use Disorder, the study may help advance scientific knowledge about how individuals adapt to uncertainty and inform future research in addiction and mental health.

Подробное описание

Alcohol Use Disorder (AUD) is associated with difficulties in decision-making and behavioral adaptation, particularly in situations involving uncertainty. Individual psychological traits may influence how people with AUD adjust their behavior when facing changing environments, but this relationship remains insufficiently understood.

This monocentric, non-interventional study aims to explore how individual traits influence adaptive processes in adults diagnosed with Alcohol Use Disorder.

Participants receiving usual care at Paul Brousse Hospital will attend a single experimental session lasting approximately 45 minutes. During this session, they will perform a computerized learning task designed to evaluate behavioral adaptation when task rules change unexpectedly. They will also complete standardized questionnaires assessing personality traits and cognitive functioning.

Behavioral performance during the task will be analyzed to measure adaptation to uncertainty and examined in relation to individual psychological characteristics.

The study does not involve medication, medical devices, or any modification of clinical care.

Первичные конечные точки

• Uncertainty Cost Index During Behavioral Adaptation Task [Срок оценки: At the end of the learning phase and at the beginning of the uncertainty phase during the single study session (approximately 45 minutes)]

Вторичные конечные точки (1)

• Correlation Between Uncertainty Cost Index and Psychometric Trait Scores [Срок оценки: During the single study session (approximately 45 minutes)]

Критерии участия

Критерии включения

• Adults aged 18 years or older
• Patients receiving care for Alcohol Use Disorder at the Psychiatry and Addiction Unit of Paul Brousse Hospital
• No objection to participation in the study

Критерии исключения

• Diagnosed neurological disorder
• Patient covered by State Medical Assistance (AME)
• Individuals under legal protection measures (guardianship, curatorship, or legal safeguard)
• Individuals deprived of liberty by judicial or administrative decision
• Pregnant or breastfeeding women
• Psychiatric disorders that could compromise proper study participation (excluding Alcohol Use Disorder)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

Франция · 1 центр

• CHU Bicêtre — Le Kremlin-Bicêtre

Идентификаторы

NCT: NCT07468825 · APHP251789 · 2025-A02680-49

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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