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Идёт набор NCT07444021

Effect of Resistance Exercise on Energy Balance and Appetite Regulation in Males and Females

Без фазы С лечением Energy Balance Energy Expenditure Males and Females Resistance Exercise

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: resistance exercise (males), resistance exercise (females).
Кому может быть актуально
Состояния в реестре: Energy Balance, Energy Expenditure, Males and Females, Resistance Exercise. Базовые параметры: 20 лет — 30 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Тайвань
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Обзор

There is growing evidence that males and females may exhibit different acute responses and long-term adaptations to exercise training. Accordingly, contemporary exercise physiology research increasingly recognizes sex as an important biological variable that may influence appetite regulation and energy balance. This year's project aims to investigate: (1) appetite regulation and energy balance following acute resistance exercise, and (2) potential sex-based differences in appetite regulation and energy balance in response to resistance exercise. Understanding both the overall effects of resistance exercise and sex-related variability in these responses is important for improving the physiological interpretation of exercise-induced changes in appetite and energy balance. Such knowledge may help to reduce heterogeneity in exercise research findings and support the development of more precise, evidence-based exercise prescriptions that are applicable to both males and females.

Вмешательства

  • Другое resistance exercise (males)
    Resistance exercises are in the following order: squat, bench press, deadlift. Each exercise consists of 3 sets with 7 repetitions, using a load of 70% 1RM with 120 sec of rest between sets.
  • Другое resistance exercise (females)
    During the early follicular phase, participants completed a standardized resistance exercise protocol consisting of squat, bench press, and deadlift, performed in a fixed order. Each exercise comprised three sets of seven repetitions at 70% of one-repetition maximum (1RM), with 120 s of rest between sets.

Первичные конечные точки

  • Subjective appetite [Срок оценки: 3 hours during each study intervention]
  • Change in acyl-Ghrelin [Срок оценки: 3 hours during each study intervention]
  • Change in PYY [Срок оценки: 3 hours during each study intervention]
  • Change in lactate [Срок оценки: 3 hours during each study intervention]
  • Energy intake [Срок оценки: The Before day, the durning day, and the day following the experiment.]
  • change in Cortisol [Срок оценки: 3 hours during each study intervention]
  • Energy expenditure [Срок оценки: The Before day, the durning day, and the day following the experiment.]
  • Energy Balance [Срок оценки: The Before day, the durning day, and the day following the experiment.]
Вторичные конечные точки (12)
  • Leeds food preference questionnaire [Срок оценки: 3 hours during each study intervention]
  • Leeds food preference questionnaire [Срок оценки: 3 hours during each study intervention]
  • 10 Ratings of Perceived Exertion (RPE) [Срок оценки: 1-hour during each exercise intervention]
  • Heart rate (HR) [Срок оценки: 3-hour during each study intervention]
  • Estradiol (E2) [Срок оценки: Baseline for each trial (female participants only).]
  • Progesterone (P4) [Срок оценки: Baseline for each trial (female participants only).]
  • Concentric Peak Velocity [Срок оценки: During each exercise condition.]
  • Concentric Mean Velocity [Срок оценки: During each exercise condition]
  • Eccentric Peak Velocity [Срок оценки: During each exercise condition]
  • Concentric Mean Power [Срок оценки: During each exercise condition]
  • Relative Concentric Mean Power [Срок оценки: During each exercise condition]
  • Concentric Work [Срок оценки: During each exercise condition]

Критерии участия

Критерии включения

  • Healthy males and females aged 20-30 years
  • Females with a regular menstrual cycle
  • Stable body weight, defined as no significant change in body weight during the past 6 months
  • Willingness to participate and provide written informed consent

Критерии исключения

  • Obesity, defined as:
  • Body mass index (BMI) > 30 kg/m²
  • Body fat percentage > 25% in males
  • Body fat percentage > 30% in females
  • Hypertension, defined as resting blood pressure > 140/90 mmHg
  • History of cardiovascular disease
  • History of cancer
  • History of liver disease
  • History of kidney disease
  • Presence of any medical condition that may interfere with study outcomes

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Рандомизированное
Модель
Перекрёстный дизайн
Маскирование
Открытое
Основная цель
Лечение

Центры проведения

Тайвань · 1 центр
  • National Taiwan Normal University — Taipei

Идентификаторы

NCT: NCT07444021 · 202412HM018

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗