The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients

Официальное название

The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients: A Randomized Controlled Study

Обзор

This study aims to contribute to clinical applications by investigating the effectiveness of functional rotation exercises on fall risk, mobility, and balance in patients diagnosed with idiopathic Parkinson's disease.

Подробное описание

This study aims to investigate the clinical effects of functional rotation exercises on fall risk and mobility in individuals with Parkinson's disease. Participants will be randomly divided into two groups: a control group and an experimental group. Demographic characteristics of all participants will be collected, and then the Timed Up and Walk Test will be used to assess fall risk, the 10-Meter Walk Test to assess mobility, and the Berg Balance Scale to assess functional balance. An extra exercise program will be applied to participants in the experimental group.

Вмешательства

• Другое conventional physiotherapy
  Conventional physiotherapy will be applied for 6 weeks, with 3 sessions per week, each session lasting approximately 40-50 minutes. Participants will be given stretching and flexibility exercises (trunk, shoulder and lower extremity muscle groups) in each session, with 10 repetitions x 15 seconds. Balance exercises (3 repetitions for 30-45 seconds in static and dynamic balance positions), walking exercises on a flat surface, and strengthening exercises (2-3 sets, 10-12 repetitions with resistan
• Другое conventional physiotherapy + exercise
  This group will receive conventional physical therapy and functional rotation exercises for 6 weeks, with 3 sessions per week, each session lasting approximately 40-50 minutes.

Первичные конечные точки

• Timed Up and Go Test [Срок оценки: 10 weeks]
• Berg Balance Test [Срок оценки: 10 weeks]

Критерии участия

Критерии включения

• Individuals with a clinical diagnosis of idiopathic Parkinson's disease (Hoehn \& Yahr stages 1-2)
• Individuals aged 50-70 years
• Mini Mental State Test score ≥ 24
• Individuals whose medical treatment has been stable in the last 6 weeks
• Individuals with stable vital signs
• Individuals who volunteer to participate in the study and understand the purpose and process of the study, and who have signed a written informed consent form

Критерии исключения

• Advanced Parkinson's disease (H\&Y 3-5)
• Severe orthopedic problems
• Vestibular system disorders
• History of serious falls in the last 6 months

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Двойное слепое

Основная цель

Лечение

Центры проведения

Turkey (Türkiye) · 1 центр

• Sancak Medical Center — Istanbul

Публикации

• Bellows S. Physiotherapy and Exercise in Parkinson's Disease. Neurol Clin. 2025 May;43(2):427-443. doi: 10.1016/j.ncl.2024.12.014. Epub 2025 Jan 24. PMID 40185529
• Zhang J, Wu M, Hou X, Song W, Li J, Teng L, Li X, Yu D, Pan J, Zhu L. Unconventional exercises for motor function in Parkinson's disease: an umbrella review of meta-analyses. Age Ageing. 2025 Mar 3;54(3):afaf062. doi: 10.1093/ageing/afaf062. PMID 40125629
• Jansen JA, Buurke TJ, van de Venis L, Weerdesteyn V, Keijsers N, Nonnekes J. Narrow-based gait in people with Parkinson's disease: Its mechanisms explored. J Parkinsons Dis. 2025 Mar;15(2):329-337. doi: 10.1177/1877718X241313333. Epub 2025 Feb 2. PMID 39973508

Идентификаторы

NCT: NCT07442370 · Uskudar91

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗