Меню
Набор скоро начнётся NCT07410767

Advanced Endoscopic Resections for Rectal Neoplasms

— Наблюдательное Rectal Cancer Rectal Adenocarcinoma Rectal Adenoma Rectal Neuroendocrine Neoplasm

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Endoscopic submucosal dissection, Endoscopic intramuscular dissection.
Кому может быть актуально
Состояния в реестре: Rectal Cancer, Rectal Adenocarcinoma, Rectal Adenoma, Rectal Neuroendocrine Neoplasm. Базовые параметры: от 18 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Польша
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Официальное название

Adoption of Advanced Endoscopic Resection Methods in the Treatment of Rectal Neoplasms

Обзор

This study evaluates how advanced endoscopic resection techniques affect treatment outcomes in adults with rectal cancer. Rectal cancer has traditionally been treated with standard abdominal surgery. Newer endoscopic techniques allow removal of selected early tumors and may reduce treatment-related complications. However, their effectiveness and safety in tumors with deeper invasion are not yet fully established. This multicenter retrospective observational study uses existing medical records from adults who underwent endoscopic or surgical resection of rectal tumors between 2015 and 2025. Researchers will analyze anonymized information on procedures performed and treatment outcomes to assess the safety and effectiveness of advanced endoscopic approaches. The results of this study may help guide treatment selection and improve care for people with rectal cancer.

Вмешательства

  • Процедура Endoscopic submucosal dissection
    Endoscopic submucosal dissection is an advanced endoscopic technique used to remove rectal tumors in one piece through the endoscope. A circumferential incision is then made in the mucosa, followed by careful dissection within the submucosal layer until the lesion is completely removed. This technique enables precise pathological assessment of tumor margins and depth of invasion and is typically used for lesions suspected to have superficial submucosal invasion without clear evidence of lymph no
  • Процедура Endoscopic intramuscular dissection
    Endoscopic intermuscular dissection is an advanced endoscopic resection technique designed for rectal tumors with suspected deeper submucosal invasion. Following mucosal incision, the dissection is intentionally performed in the plane between the inner circular and outer longitudinal muscle layers of the rectal wall. This allows deeper en bloc tumor removal compared with conventional endoscopic submucosal dissection. The goal of this technique is to achieve complete resection while potentially a

Первичные конечные точки

  • Major intraprocedural bleeding rate [Срок оценки: During the procedure]
  • Intraprocedural perforation rate [Срок оценки: During the procedure]
  • Delayed bleeding rate [Срок оценки: Within 28 days after the procedure]
  • Delayed perforation rate [Срок оценки: Within 14 days after the procedure]
  • Post-coagulation syndrome rate [Срок оценки: Within 28 days following the procedure]
  • The need for emergency interventions [Срок оценки: Within 30 days after the procedure]
  • Procedure-related mortality rate [Срок оценки: Within 30 days after the procedure]
Вторичные конечные точки (5)
  • En bloc resection rate [Срок оценки: Intraprocedural]
  • Complete resection rate [Срок оценки: Within 30 days after the procedure]
  • Procedure time [Срок оценки: Intraprocedural]
  • Length of hospital stay [Срок оценки: Within 30 days after the procedure]
  • The need for additional treatment [Срок оценки: Within 12 months after the procedure]

Критерии участия

Критерии включения

  • Patients with rectal neoplasms treated by advanced endoscopic resection

Критерии исключения

  • hybrid resection performed
  • full-thickness resection performed
  • essential procedural or outcome data were unavailable

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения
Когортное

Центры проведения

Польша · 1 центр
  • Jagiellonian University in Krakow — Krakow

Идентификаторы

NCT: NCT07410767 · 1072.6120.2.63.2026

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗