Adaptation and Validation of the Hypomanic Personality Scale (HPS-6) to Romanian

Официальное название

Adaptation and Validation of the Hypomanic Personality Scale (HPS-6) to Romanian.

Обзор

The HPS-6 (Hypomanic Personality Scale, 6 item version) could prove to be a valuable candidate for screening measures of high risk individuals. In the following study, we aim to validate and adapt the HPS-6 for the Romanian population.

Подробное описание

Bipolar disorder (BD) is a chronic, debilitating disorder, affecting approximately 2.4% of the global population. Inaccurate diagnosis leads to inappropriate management of the disorder as well as unsuitable medication prescription. On average, it can take a BD individual 5 to 10 years to receive an accurate diagnosis and receive competent treatment. Across the European Union (EU) Romania has the lowest prevalence of psychiatric disorders, 14.3%. Unfortunately, these positive estimates are related to the severe stigma linked to poor mental health in the Romanian population. Although the average length of a psychiatric stay in the EU spans across 24.3 days, Romania's average is 17.7. Poor infrastructure and lack of personnel in the Romanian healthcare system might be partially responsible. Therefore, brief, validated screening measures for complex diagnoses are necessary.

Вмешательства

• Диагностический тест Hypomanic Personality Scale - 6
  A brief instrument, such as the HPS-6, with high specificity can help navigate specialists towards a correct diagnosis or recognize risk patterns in Bipolar Spectrum Individuals.

Первичные конечные точки

• Hypomanic Personality Scale - 6 (HPS-6) [Срок оценки: Baseline and one month later for re-test measures (in order to account for test-retest reliability)]
• Mood Disorder Questionnaire (MDQ) [Срок оценки: Baseline]
• Behavioral Inhibition System / Behavioral Activation System scales (BISBAS) [Срок оценки: One month after Baseline]
• Positive and Negative Affect Schedule (PANAS) [Срок оценки: One month after Baseline.]
• Negative Urgency, Premeditation, Perseverance, Sensations Seeking, and Positive Urgency - Impulsive Behavior Scale (UPPS-P) [Срок оценки: One month after Baseline]
• Affective Lability Scale - Short Form (ALS-18) [Срок оценки: One month after Baseline]
• Positive Overgeneralization (POG) [Срок оценки: One month after Baseline.]
• Altman Self-Rating Mania Scale (ASRM) [Срок оценки: Baseline]
• Food Neophobia Scale (FNS) [Срок оценки: Baseline]
• Patient Health Questionnaire-9 (PHQ-9) [Срок оценки: Baseline]

Вторичные конечные точки (2)

• Psychiatric Diagnostic Screening Questionnaire (PDSQ) [Срок оценки: Baseline]
• Suicide Behavior Questionnaire-Revised (SBQ-R) [Срок оценки: Baseline]

Критерии участия

Критерии включения

• 18-50 years of age
• Not at high risk of suicide (current)
• Not high SUDs / AUDs (current)
• Native Romanian speaker
• Cognitive abilities intact (reading comprehension of items)

Критерии исключения

• High risk of suicide (current)
• High SUDs / AUDs (current)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Не применимо

Модель

Последовательный дизайн

Маскирование

Тройное слепое

Основная цель

Скрининг

Центры проведения

Румыния · 1 центр

• Babeș-Bolyai University — Cluj-Napoca

Публикации

• Wang HR, Woo YS, Ahn HS, Ahn IM, Kim HJ, Bahk WM. THE VALIDITY OF THE MOOD DISORDER QUESTIONNAIRE FOR SCREENING BIPOLAR DISORDER: A META-ANALYSIS. Depress Anxiety. 2015 Jul;32(7):527-38. doi: 10.1002/da.22374. Epub 2015 May 22. PMID 26010478
• Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (1999). Patient Health Questionnaire-9 (PHQ-9). APA PsycTests, 10. https://doi.org/10.1037/t06165-000
• Manea L, Gilbody S, McMillan D. A diagnostic meta-analysis of the Patient Health Questionnaire-9 (PHQ-9) algorithm scoring method as a screen for depression. Gen Hosp Psychiatry. 2015 Jan-Feb;37(1):67-75. doi: 10.1016/j.genhosppsych.2014.09.009. Epub 2014 Sep 23. PMID 25439733
• Levis B, Benedetti A, Thombs BD; DEPRESsion Screening Data (DEPRESSD) Collaboration. Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis. BMJ. 2019 Apr 9;365:l1476. doi: 10.1136/bmj.l1476. PMID 30967483
• Pliner P, Hobden K. Development of a scale to measure the trait of food neophobia in humans. Appetite. 1992 Oct;19(2):105-20. doi: 10.1016/0195-6663(92)90014-w. PMID 1489209
• Rabadán, A., & Bernabéu, R. (2021). A systematic review of studies using the Food Neophobia Scale: Conclusions from thirty years of studies. Food Quality and Preference, 93, 104241. https://doi.org/10.1016/j.foodqual.2021.104241
• Sorokowski, P., Sorokowska, A., Misiak, M., & Roberts, S. C. (2023). Developmental changes in food and non-food odor importance-Data from Scotland and Pakistan. Food Quality and Preference, 111, 104963.
• Meyer, T. D., & Baur, M. (2009). Positive and negative affect in individuals at high and low risk for bipolar disorders. Journal of Individual Differences, 30(3), 169-175.

Идентификаторы

NCT: NCT07399626 · 1068/10.12.2025

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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