Efficiency of Self Extracted Tooth Graft in Extraction Socket : A Clinical and Radiographic Study

Официальное название

Evaluating the Efficacy of Autogenous Tooth Graft (ATG) Material in Socket Preservation: A Clinical and Radiographic Study.

Обзор

This is the clinical trial. The goal of this clinical trial is to test whether self extracted tooth graft (autogenous tooth graft ) able to preserved the extraction socket effectively. Our aim is to answer is there any difference in dimensional changes in extraction socket in clinically and radiographically Researchers will compare autogenous tooth graft with self-healing extraction socket in radiographic and clinical measurement. Participant will be randomly allocated into 2 groups ( Test or controlled group) Test group will be autogenous tooth grafting post extraction. After removed any caries, calculus and any gilling material, the extracted tooth will be grind with grinder and processed using BONMAKER machine. (which the bone graft is washed with hydrogen peroxide, hydrogen chloride and alcohol isopropyl) and controlled group will be self healing group. Both group will withdraw 20cc blood for PRF ( Plasma rich fibrin) membrane and place into the socket and secured with suture. They will be reviewed post extraction 1 week ( to ensure there is no infection ) , 2 week ( for suture removal ) , 1 months ( For clinical measurement) , 3 months (For clinical and radiographic measurement) and 6 months (For radiographic measurement).

Вмешательства

• Процедура autogenous tooth graft
  Extracted tooth will be grind and processed into bone graft . This bone graft material will grafted into the extraction socket

Первичные конечные точки

• Socket dimensional changes in autogenous tooth graft group and self healing group [Срок оценки: 6 months]

Вторичные конечные точки (1)

• Volumetric changes in autogenous tooth group and self healing group [Срок оценки: 6 months]

Критерии участия

Критерии включения

• Age> or equal to 18 years old
• Presence of adjacent teeth to the extraction site
• Healthy ,or well controlled systemic disease
• Lower and upper incisors, lower premolar/ first molar
• Full mouth plaque score < 15%
• Adequate space for a dental implant restoration \*Patient with previous diagnosis of periodontitis will be required to have a successfully completed course of periodontal treatment before enrolment.

Критерии исключения

• Smokers and vapers
• Acute infection or sinus tract in relation to the tooth that require extraction
• Pregnant or lactating women
• Patient received antibiotic for past 1 month
• Loss of more than 50% buccal or lingual /palatal bone at the time of extraction
• Patient on medication that altered bone metabolism or bone healing such as bisphosphonates, chemotherapeutic drugs or immunosuppressive agents

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Двойное слепое

Основная цель

Лечение

Центры проведения

Малайзия · 1 центр

• Faculty of Dentistrty — Jenjarum

Публикации

• Elfana A, El-Kholy S, Saleh HA, Fawzy El-Sayed K. Alveolar ridge preservation using autogenous whole-tooth versus demineralized dentin grafts: A randomized controlled clinical trial. Clin Oral Implants Res. 2021 May;32(5):539-548. doi: 10.1111/clr.13722. Epub 2021 Mar 1. PMID 33565656

Идентификаторы

NCT: NCT07394634 · RMC/JANUARY/2025/EC07

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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