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Набор скоро начнётся NCT07391046

Integrating Vaccination Into Hospital Care Pathways for Vulnerable Patients

— Наблюдательное Chronic Disease Immunocompromised HIV Infection Chronic Kidney Disease

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Hospital-Based Vaccination Pathway.
Кому может быть актуально
Состояния в реестре: Chronic Disease, Immunocompromised, HIV Infection, Chronic Kidney Disease. Базовые параметры: от 18 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Список центров уточняется — проверьте первичный протокол.
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Integrating Vaccination Into Hospital Care Pathways for Vulnerable Patients: A Scalable and Sustainable Model

Обзор

AMBU-VAX is a prospective, single-center observational study designed to develop and implement an organizational model for delivering recommended vaccinations within a hospital setting. The study targets adult and elderly patients with chronic diseases or immunocompromising conditions who are eligible for vaccination according to national immunization guidelines. Vaccination is actively proposed during outpatient visits, hospital admissions, or at discharge and, when accepted, administered within the hospital or coordinated with local public health vaccination services. The study aims to evaluate the feasibility, uptake, and completion of hospital-based vaccination pathways and to support integration between hospital and territorial prevention services for vulnerable populations.

Подробное описание

Vaccination coverage among hospitalized and chronically ill patients remains suboptimal despite strong national and international recommendations. Hospital settings represent a strategic opportunity to identify vulnerable patients, reduce missed vaccination opportunities, and improve access to preventive services.

AMBU-VAX is a prospective observational study conducted at Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome. The study targets adult patients affected by chronic diseases or immunocompromising conditions eligible for recommended vaccinations according to the Italian National Immunization Plan 2023-2025.

Patients are identified during outpatient visits, hospital admissions, or at discharge. Vaccination is actively proposed and, when accepted, administered within the hospital vaccination clinic or ward. When appropriate, patients are referred to local vaccination services to complete their immunization schedule.

Primary outcomes include vaccination offer, vaccine uptake, number of administered doses, and completion of vaccination pathways within the hospital setting. Secondary outcomes include reasons for vaccine refusal and referral to territorial vaccination services.

The study aims to assess the feasibility, effectiveness, and sustainability of a hospital-based vaccination model that can be replicated in other healthcare settings.

Вмешательства

  • Биопрепарат Hospital-Based Vaccination Pathway
    Integration of vaccination counseling, prescription, and administration into hospital care pathways for vulnerable adult patients, including coordination with local public health vaccination services. No experimental vaccine is used; all vaccines are administered according to national guidelines.

Первичные конечные точки

  • Vaccination Offer Rate [Срок оценки: 12 months]
  • Vaccination Uptake Rate [Срок оценки: 12 months]
  • Number of Administered Vaccine Doses [Срок оценки: 12 months]
  • Completion of Hospital-Based Vaccination Pathway [Срок оценки: 12 months]
Вторичные конечные точки (3)
  • Reasons for Vaccine Refusal [Срок оценки: 12 months]
  • Referral to Territorial Vaccination Services [Срок оценки: 12 months]
  • Specialist Evaluation for Contraindications [Срок оценки: 12 months]

Критерии участия

Критерии включения

  • Adults aged ≥18 years
  • Presence of at least one chronic or immunocompromising condition eligible for vaccination according to national guidelines
  • Written informed consent provided

Критерии исключения

  • Age <18 years
  • Conditions not included among the predefined eligibility criteria

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения
Когортное

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT07391046 · 8272

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗