Exploring the Decision to Drink (More) Alcohol Following Manipulations of Stress and Social Context
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Stress, Social Context.
- Кому может быть актуально
- Состояния в реестре: Psychological Stress, Social Interaction. Базовые параметры: 21 лет — 50 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- США
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Обзор
This preregistration documents an experiment examining the effects of acute stress and social context on alcohol-related decision-making. The study uses a 2x2 factorial design (stress vs. control × social vs. alone) with dyadic recruitment.
Подробное описание
Behavioral data:
Our first set of hypotheses tests whether the decision is influenced by stress and social context:
H1a: Stress affects the decision between alcoholic and non-alcoholic drinks, so that participants in the stress conditions choose alcoholic over non-alcoholic drinks more often compared to participants in the no stress conditions.
H1b: Social context affects the decision between alcoholic and non-alcoholic drinks, so that participants in the social conditions choose alcoholic over non-alcoholic drinks more often compared to participants in the alone conditions.
H1c: We test two competing predictions:
(I) The effect of stress on the decision between alcohol and non-alcoholic drinks is modulated by social context, so that the effect of stress is stronger for participants that are in the social condition.
(II) The effect of stress on the decision between alcohol and non-alcoholic drinks is modulated by social context, so that the effect of stress is weaker for participants that are in the social condition
Drift diffusion modeling:
Our second set of hypotheses test how the decision might be influenced by stress and social context:
H2a: Stress affects the bias (but not the drift rate or boundary) parameter of the drift diffusion model, so that the bias parameter is more positive for participants in the stress conditions.
H2b: Social context affects the bias (but not the drift rate or boundary) parameter of the drift diffusion model, so that the bias parameter is more positive for participants in the social conditions.
H2c: Stress and social context have an interactive effect on the bias (but not the drift rate or boundary) parameter of the drift diffusion model, so that the bias parameter is either more or less positive for stressed participants who are in the social condition (in line with H1c).
Вмешательства
- Другое Stress
Participants randomly assigned to the stress condition will undergo the standard protocol of the Trier Social Stress Test. Participants randomly assigned to the control condition will undergo a validated, non-stressful control procedure mirroring the TSST. - Другое Social Context
Participants randomly assigned to the social condition will make decisions about consuming alcohol with a known peer. Participants randomly assigned to the control condition will make decisions about consuming alcohol alone.
Первичные конечные точки
- Proportion of choices for alcoholic over non-alcoholic drinks. [Срок оценки: 5 minutes]
Критерии участия
Критерии включения
- Drinking alcohol at least once a week
- Consuming 4 (female) or 5 (male) drinks in one occasion at least once a month
Критерии исключения
- Currently pregnant or trying to become pregnant
- Past or current treatment for alcohol use
- Past or current medical condition that contraindicates alcohol use
- Past or current reaction to alcohol that contraindicates alcohol use
- Past or current medication that contraindicates alcohol use
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Да
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Факторный дизайн
- Маскирование
- Открытое
- Основная цель
- Фундаментальное исследование
Центры проведения
США · 1 центр
- University of Washington — Seattle
Идентификаторы
NCT: NCT07390084 · STUDY00023737 · R00AA030591