Soluble and Osmotic Fibre (SOLOS) Diet for Constipation
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Diet.
- Кому может быть актуально
- Состояния в реестре: Constipation, Constipation - Functional, Constipation Chronic Idiopathic, Constipation Predominant Irritable Bowel Syndrome. Базовые параметры: 18 лет — 70 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Сингапур
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
The Soluble and Osmotic Fibre (SOLOS) Diet for Functional Bowel Disorders With Constipation
Обзор
This research aims to study the dual effectiveness of incorporating soluble fibre and osmotic carbohydrates (SOLOS), with or without restricting fructans and GOS, and present novel findings in managing GI symptoms in patients with functional bowel disorders with constipation. These findings may also support researchers and clinicians in shaping new dietary approaches in the management of general constipation symptoms.
Подробное описание
Aims: This retrospective clinical audit study aims to evaluate the effectiveness of dietary advice promoting increased intake of soluble fibre and poorly absorbed (osmotic) carbohydrates, with or without restriction of fructans and galacto-oligosaccharides (GOS), on adult patients (18-70 years old) with functional bowel disorders with constipation from the UK by comparing to baseline scores for severity and frequency of gastrointestinal symptoms and stool output.
Hypothesis: The dietary advice promoting increased intake of soluble fibre and osmotic sugars will produce a significant change from baseline in gastrointestinal symptoms and stool output in adult patients (18-70 years old) with functional bowel disorders with constipation from the UK.
Methodology: The study population will include all patients who have consulted with the Principal Investigator, a specialist gastroenterology dietitian between January 2021 and December 2025. All patients who have met the inclusion criteria will then form the research sample. Eligible subjects' data and study variables will be extracted from patient letters and clinical management records without direct patient contact. These study variables include the frequency and severity of the patients' symptoms at their initial appointment and follow-up appointment if available. Anthropometric data such as height and weight will also be obtained. The compiled data will then be analysed by conducting statistical tests, specifically the paired t-test, which will produce descriptive statistics that will interpret the effectiveness of the SOLOS diet on patients with functional bowel disorders with constipation.
Applications: To date, there has not been any study studying the dual effects of soluble fibre and osmotic carbohydrates consumption on alleviating constipation-related symptoms in patients with functional bowel disorders with constipation. Therefore, this research aims to present novel findings that can advance existing dietary management of functional bowel disorders with constipation. These results are expected to deepen understanding and research in food manufacturing and clinical nutrition.
Вмешательства
- Другое Diet
Dietary advice combining increased intake of dietary sources of soluble fibres and osmotic sugars in improving constipation symptoms.
Первичные конечные точки
- Stool frequency [Срок оценки: January 2021 to December 2025]
- Stool form [Срок оценки: January 2021 to December 2025]
- Gastrointestinal Symptom Frequency [Срок оценки: January 2021 to December 2025]
- Gastrointestinal Symptom Severity [Срок оценки: January 2021 to December 2025]
Критерии участия
Критерии включения
- Presented with symptoms of FC, IBS-C, or SIBO-C
- Were aged 18 to 70 years old. (Research focus is on adult patients, excluding older adults and children)
- Date of baseline (first) and follow-up appointments ranged from January 2021 to December 2025
- Did not attend follow-up appointments (Data would be treated as "intention to treat" and data points were carried forward for conservative analysis).
Критерии исключения
- Had no history of constipation-related symptoms (Does not relate to research question's population or outcome)
- Started treatment before January 2021
- Were not due for follow-up before the end of December 2025
- Symptom and stool data inadequately recorded
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
Сингапур · 1 центр
- Singapore Institute of Technology — Singapore
Идентификаторы
NCT: NCT07388589 · RECAS-0723-IRB