Predictors of Laparoscopy Conversion in Adhesive Small Bowel Obstruction
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Laparoscopic adhesiolysis, Laparotomic adhesiolysis.
- Кому может быть актуально
- Состояния в реестре: Adhesive Small Bowel Obstruction. Базовые параметры: от 18 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Россия
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Predictors of Laparoscopy Conversion in the Treatment of Adhesive Small Bowel Obstruction
Обзор
The goal of this observational study is to reveal predictors of unsuccessfull laparoscopic intervention in adult patients with adhesive small bowel obstruction. The main question it aims to answer is: are there any strong predictors of laparoscopy conversion in patients with small bowel obstruction, caused by intraabdominal adhesions.
Подробное описание
Considering the undeniable advantages of laparoscopic interventions over laparotomic ones, the question of choosing a surgical approach in patients with acute adhesive intestinal obstruction can be reformulated as follows: in what situations is endovideosurgical intervention generally appropriate and feasible? A laparoscopic approach to severely distended bowel loops and widespread adhesions may increase the risk of serious complications. Indeed, some authors report intestinal injury in 6.3-26.9% of patients undergoing laparoscopic adhesiolysis for acute adhesive intestinal obstruction, which is statistically significantly higher than the same rate in patients operated on using a traditional approach. Therefore, a priority should be addressing the issue of adequately selecting patients who, based on a number of clinical indicators, are suitable for laparoscopic surgery or, at least, have no contraindications. While some parameters, such as acute cardiovascular or respiratory failure and pregnancy in the third trimester, can be defined as absolute contraindications to endovideosurgical access, a number of clinical and instrumental indicators are debatable. Despite the fact that this issue has been extensively covered in the literature, and the list of predictors of unsuccessful laparoscopic adhesiolysis is currently quite impressive, a standardized approach to access selection is lacking or is determined largely intuitively.
The aim of this work is to determine reliable anamnestic, clinical and instrumental signs that would indicate a high risk of conversion of the laparoscopic intervention in patients with acute adhesive intestinal obstruction.
The study is planned to be a multicenter, retrospective case-control study. Clinical data will be collected at four medical institutions in St. Petersburg. The medical records of patients who underwent emergency and urgent surgery for acute adhesive intestinal obstruction will be analyzed.
Вмешательства
- Процедура Laparoscopic adhesiolysis
Dissection of intra-abdominal adhesions performed laparoscopically in accordance with the principles adopted in the medical institution. - Процедура Laparotomic adhesiolysis
Traditional adhesiolysis, performed via laparotomy after unsuccessfull attempt of endovideosurgical approach.
Первичные конечные точки
- Rate of succesfull laparoscopic interventions [Срок оценки: At the discharge from the hospital (assessed up to 10 days)]
Вторичные конечные точки (7)
- Diameter of intestinal loops [Срок оценки: Perioperative]
- Known or suspected complex adhesive process [Срок оценки: Perioperative]
- Number of laparotomy operations [Срок оценки: Perioperative]
- Ischemia or necrosis of the intestine [Срок оценки: Perioperative]
- Obstruction level [Срок оценки: Perioperative]
- Duration of acute intestinal obstruction [Срок оценки: Perioperative]
- Time of day at the start of the surgical intervention [Срок оценки: Perioperative]
Критерии участия
Критерии включения
- patients underwent emergency and urgent surgery for acute adhesive intestinal obstruction
- the surgery was performed laparoscopically
- the surgery was initiated laparoscopically and completed via laparotomy
Критерии исключения
- acute adhesive intestinal obstruction in the hernial sac
- pregnant in the third trimester
- patients with severe cardiovascular or respiratory failure
- patients with hemodynamic shock
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Модель наблюдения
- Случай-контроль
Центры проведения
Россия · 7 центров
- Kazan Federal University — Kazan'
- City Clinical Hospital No. 4 — Perm
- Almazov National Medical Research Centre — Saint Petersburg
- Mariinskaya Hospital — Saint Petersburg
- Saint-Petersburg I.I. Dzhanelidze research institute of emergency medicine — Saint Petersburg
- The City Hospital of the Holy Martyr Elizabeth — Saint Petersburg
- City Clinical Hospital No. 40 — Yekaterinburg
Идентификаторы
NCT: NCT07350447 · 14071979