Меню
Идёт набор NCT07340385

Physiological and Biochemical Responses to Blood Flow Restriction Training

— Наблюдательное Healthy Individuals Trained Athletes

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Blood Flow Restriction Training.
Кому может быть актуально
Состояния в реестре: Healthy Individuals, Trained Athletes. Базовые параметры: 18 лет — 40 лет · Мужчины.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Turkey (Türkiye)
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Официальное название

The Effects of Training History on Physiological and Biochemical Responses in Blood Flow Restriction Strength Training

Обзор

This study is designed to examine the short-term and long-term effects of blood flow restriction exercise training on physiological and biochemical markers in individuals who are new to strength training and in experienced athletes training at different load levels. This exercise method involves placing a special inflatable cuff around the upper part of the thigh. The cuff partially limits blood flow to the area, which helps the muscles work more effectively during exercise. The cuff will be applied only to the individual's dominant leg (the leg you use more often in daily activities), but all exercises will be performed using both legs. The exercise program will last for a total of six weeks and will be carried out twice per week. The pressure applied by the cuff will be individually adjusted based on each participant's physical characteristics to ensure safety and comfort. The study will include a total of 30 healthy participants aged between 18 and 40 years. Participants will be divided into two groups: individuals who have recently started strength training and experienced athletes with different levels of training experience.

Вмешательства

  • Другое Blood Flow Restriction Training
    Adaptation to blood flow restriction exercise training and the individually tailored occlusion pressure will be determined during the initial sessions. Occlusion pressure will be assessed while the participant is in a supine position by inflating a pneumatic cuff placed on the thigh until the tibial artery pulse is no longer detectable, which will be confirmed using a handheld Doppler device. To ensure safe adaptation to the training protocol, the pressure applied during the first two training s

Первичные конечные точки

  • Muscle Thickness [Срок оценки: Baseline and after 6 weeks of training]
  • Blood Biomarkers [Срок оценки: Blood samples will be collected at three time points: before and immediately after the third training session to assess acute responses, and at the end of the 6-week training period to assess long-term effects.]

Критерии участия

Критерии включения

  • Voluntary participation of healthy adults
  • Age between 18 and 40 years
  • No history of orthopedic pathology or current symptoms affecting the lower extremities
  • For individuals with prior training experience: engagement in strength training at least two days per week for the past year across different sports disciplines
  • For individuals new to strength training: no regular participation in strength training within the past six months

Критерии исключения

  • History of hypertension, cardiovascular diseases, peripheral vascular diseases, deep vein thrombosis, neurological disorders, obesity, or a diagnosis of diabetes
  • Current or previous diagnosis of cancer
  • Individuals who do not consent to participate in the study

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Модель наблюдения
Другое

Центры проведения

Turkey (Türkiye) · 1 центр
  • Afyonkarahisar Health Sciences University — Afyonkarahisar

Публикации

  • Nielsen JL, Aagaard P, Prokhorova TA, Nygaard T, Bech RD, Suetta C, Frandsen U. Blood flow restricted training leads to myocellular macrophage infiltration and upregulation of heat shock proteins, but no apparent muscle damage. J Physiol. 2017 Jul 15;595(14):4857-4873. doi: 10.1113/JP273907. Epub 2017 Jun 23. PMID 28481416
  • Centner C, Zdzieblik D, Dressler P, Fink B, Gollhofer A, Konig D. Acute effects of blood flow restriction on exercise-induced free radical production in young and healthy subjects. Free Radic Res. 2018 Apr;52(4):446-454. doi: 10.1080/10715762.2018.1440293. Epub 2018 Mar 15. PMID 29448855
  • Franchi MV, Longo S, Mallinson J, Quinlan JI, Taylor T, Greenhaff PL, Narici MV. Muscle thickness correlates to muscle cross-sectional area in the assessment of strength training-induced hypertrophy. Scand J Med Sci Sports. 2018 Mar;28(3):846-853. doi: 10.1111/sms.12961. Epub 2017 Sep 21. PMID 28805932

Идентификаторы

NCT: NCT07340385 · 2025/9

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗