Cardiovascular Effects of Music Versus Guided Mindfulness

Music and mindfulness-based practices, such as meditation and breathing exercises, are well-established non-pharmacological interventions known to positively influence both physiological and psychological health. They are utilized for their ability to reduce stress and promote relaxation by modulating autonomic nervous system activity, which in turn influences the cardiovascular system. This modulation has been associated with reductions in markers of physiological stress, such as blood pressure and heart rate.

Cardiovascular influences of music and mindfulness have been leveraged in numerous medical procedures for enhancing comfort and tolerability, as well as mental well-being. However, despite the widespread use and documented physiological effects of music and mindfulness-based interventions, there is a lack of research directly comparing their effects. Furthermore, there is a relative lack of high-quality randomized trials examining the effects of music and mindfulness on parameters such as blood pressure and heart rate.

This randomized crossover study will examine the cardiovascular impact of listening to a curated music playlist versus participating in a guided mindfulness session in a healthy population to determine whether music produces greater reductions in blood pressure and heart rate than guided mindfulness.

Each participant will attend a single 3-hour study visit, during which they will take part in two sessions. One session involves listening to a carefully selected music playlist, and the other involves participating in a guided mindfulness exercise. The order of the sessions will be random. Blood pressure and heart rate will be measured throughout the study visit, and participants will be asked to complete questionnaires measuring anxiety, experience with music and mindfulness, tendency to become deeply engaged, and enjoyment of each session.

The primary aim is to compare changes in systolic blood pressure, diastolic blood pressure, and heart rate between curated music playlist and guided mindfulness interventions, using an automated oscillometric upper arm blood pressure monitor with measurements taken at 10-minute intervals.

By investigating the physiological effects of music versus guided mindfulness on hemodynamic responses in a healthy population, this study will provide critical insight into the distinct and shared autonomic effects of these two non-pharmacological interventions. Understanding the cardiovascular effects of music and guided mindfulness will inform evidence-based guidelines for integrating these interventions into clinical and research protocols. As non-invasive therapeutic tools, both music and mindfulness hold promise for enhancing patient care across diverse settings.

• Changes in Beat-to-Beat Blood Pressure (Finapres NOVA) [Срок оценки: 0 to 40 minutes during each 40-minute intervention session.]
• Changes in Heart Rate (Finapres NOVA, Electrocardiogram-derived) [Срок оценки: 0 to 40 minutes during each 40-minute intervention session.]
• Change from Baseline in STAI-Y 1 [Срок оценки: Baseline and immediately after each of the two 40-minute intervention sessions during the single study visit.]
• Change from Baseline in Edmonton Symptom Assessment System (ESAS) [Срок оценки: Baseline and immediately after each of the two 40-minute intervention sessions during the single study visit.]
• Barcelona Music Reward Questionnaire (BMRQ) [Срок оценки: Baseline]
• MUSE questionnaire [Срок оценки: Baseline]
• Mindfulness Adherence Questionnaire (MAQ) [Срок оценки: Baseline]
• Modified Tellegen Absorption Scale (MODTAS) [Срок оценки: Baseline]
• Subjective Enjoyment (Visual Analogue Scale and Open-Ended Questions) [Срок оценки: Immediately after each of the two 40-minute intervention sessions during the single study visit.]