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Идёт набор NCT07337889

Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder

Без фазы С лечением Borderline Personality Disorder Borderline Personality Disorder (BPD) Bipolar Disorder (BD)

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Relationship-use questionnaire.
Кому может быть актуально
Состояния в реестре: Borderline Personality Disorder, Borderline Personality Disorder (BPD), Bipolar Disorder (BD). Базовые параметры: 18 лет — 45 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Франция
Следующий шаг
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Обзор

This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a "Relationship Use Disorder." The research proposes that BPD shares key features with behavioral addictions, specifically addiction to interpersonal relationships. The study builds upon previous findings suggesting that individuals with BPD experience intense emotional dysregulation, including negative self-perception, shame, and a compulsive need for external validation. This addiction to relationships, much like substance use disorders, is thought to contribute significantly to the difficulties faced by these individuals, including interpersonal conflicts, self-destructive behaviors, and emotional instability. The study seeks to demonstrate that the relational difficulties central to BPD meet the diagnostic criteria for addiction as defined by the DSM-5. It will also explore how these relational struggles are mediated by dysfunctional self-perception and whether they are linked to behaviors such as compulsive sexual behaviors (CSBD) or suicidal tendencies. Additionally, the research will investigate the relationship between addiction to relationships and neurobiological factors, including endorphin levels, in individuals with BPD compared to those with bipolar disorder and healthy controls. The hypothesis is that individuals with BPD will exhibit higher levels of relationship addiction, with this addiction being tied to their perception of self-worth and emotional experiences in relationships. This innovative approach aims to refine the understanding of BPD, reduce stigma, and improve treatment strategies by providing scientific evidence supporting the conceptualization of BPD as a "Relationship Use Disorder."

Вмешательства

  • Другое Relationship-use questionnaire
    Questionnaire adapted from the 'Substance Use Disorders' section of the DSM-5: Disorder related to the use of close relationships

Первичные конечные точки

  • Relational Addiction [Срок оценки: Measured at baseline]
Вторичные конечные точки (12)
  • Function Acquisition Speed Test (FAST) [Срок оценки: Measured at baseline]
  • Visual Analogue Scale (VAS) for Perceived Alignment with BPD [Срок оценки: Measured at baseline]
  • Love Addiction Inventory (LAI) [Срок оценки: Measured at baseline]
  • Beta-Endorphin Levels [Срок оценки: Measured at baseline]
  • Dysfunctional Self-Perception and Related Indicators (SES) [Срок оценки: Measured at baseline]
  • Dysfunctional Self-Perception and Related Indicators (RSES) [Срок оценки: Measured at baseline]
  • Dysfunctional Self-Perception and Related Indicators (ESS) [Срок оценки: Measured at baseline]
  • Dysfunctional Self-Perception and Related Indicators (VAS) [Срок оценки: Measured at baseline]
  • Painful Experiences Related to the Relational Object (MSR) [Срок оценки: Measured at baseline]
  • Painful Experiences Related to the Relational Object (ESUL) [Срок оценки: Measured at baseline]
  • Painful Experiences Related to the Relational Object (RSQ) [Срок оценки: Measured at baseline]
  • Compulsive Sexual Behavior Disorder [Срок оценки: Measured at baseline]

Критерии участия

Критерии включения

  • General : aged 18-45
  • Specific :
  • Borderline personality disorder (BPD)assessed by SCID, without bipolar disorder
  • Bipolar disorder (assessed by SCID), without BPD (evaluated by SCID)
  • Healthy controls with no psychiatric disorders (screened by SCID).

Критерии исключения

  • Psychotic disorders (evaluated by SCID)
  • lack of informed consent
  • Not affiliated with social security
  • Under judicial or administrative confinement or involuntary hospitalization
  • Protected by law (e.g., under guardianship)
  • Pregnancy or breastfeeding
  • Inability to understand, speak, or write in French
  • Inability to understand the study's purpose or methodology
  • Excluded from another study during the exclusion period
  • Participants who have received over €6000 in annual indemnities
  • For Bipolar Participants (without BPD) : Current moderate or severe depressive episode (BDI score > 18) or Current hypomanic/manic episode (YMRS < 12)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Нерандомизированное
Модель
Параллельные группы
Маскирование
Открытое
Основная цель
Другое

Центры проведения

Франция · 1 центр
  • CHU Montpellier — Montpellier

Идентификаторы

NCT: NCT07337889 · RECHMPL24_0194

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗