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Идёт набор NCT07278700

The Fever Clinic Acute Respiratory Cohort

— Наблюдательное Acute Respiratory Infections Febrile Illnesses Community-acquired Pneumonia Viral Respiratory Tract Infections

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: No intervention involved.
Кому может быть актуально
Состояния в реестре: Acute Respiratory Infections, Febrile Illnesses, Community-acquired Pneumonia, Viral Respiratory Tract Infections. Базовые параметры: от 18 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Китай
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

The Fever Clinic Acute Respiratory Cohort (FACTS): A Prospective Real-World Cohort Study of Patients Presenting to Fever Clinics: Clinical Features, Laboratory and Radiographic Findings, and Long-Term Outcomes of Acute Respiratory Infections

Обзор

This prospective cohort study aims to characterize the natural progression and outcomes of acute respiratory infections among patients presenting to fever clinics. At enrollment, patients' clinical symptoms, laboratory findings, and chest imaging data will be collected. Longitudinal follow-up will be conducted to evaluate disease progression, complications, and long-term outcomes. As an observational study, no interventions are involved; all patients receive routine clinical management as directed by their attending physicians. This real-world study design enables the assessment of the natural course of acute respiratory infections and the identification of factors associated with clinical outcomes.

Подробное описание

This prospective cohort study aims to characterize the natural history and outcomes of acute respiratory infection in patients presenting to fever clinics. Upon enrollment, patients' clinical symptoms, laboratory parameters, and chest imaging data will be collected. Subsequent longitudinal follow-up will be performed to assess disease progression, complications, and long-term outcomes.

As an observational study, no interventions are implemented; all patients receive standard-of-care management as determined by their attending physicians. This real-world study design allows for the evaluation of the natural progression of acute respiratory infections and the identification of factors associated with clinical outcomes.

Вмешательства

  • Другое No intervention involved
    This is a observational study so no intervention involved.

Первичные конечные точки

  • Proportion of Participants Hospitalized for Pneumonia [Срок оценки: 30 days]
Вторичные конечные точки (10)
  • Rate of Symptom Resolution at 24 Hours [Срок оценки: 24 hours]
  • Rate of Symptom Resolution at 7 Days [Срок оценки: 7 days]
  • Time to Sustained Symptom Resolution [Срок оценки: 30 days]
  • All-cause Mortality Rate at 30 Days [Срок оценки: 30 days]
  • Intensive Care Unit (ICU) Admission Rate at 30 Days [Срок оценки: 30 days]
  • Change in White Blood Cell (WBC) Count [Срок оценки: Baseline, Day 3]
  • Normalization Rate of C-reactive Protein (CRP) [Срок оценки: Baseline, Day 7]
  • Change in Procalcitonin (PCT) Level [Срок оценки: Baseline, Day 3]
  • Incidence of Acute Exacerbation of Underlying Chronic Diseases [Срок оценки: 30 days]
  • Rate of Unplanned Medical Visits [Срок оценки: 30 days]

Критерии участия

Критерии включения

  • Age ≥ 18 years (based on official identification document).
  • Presence of fever at the time of visit or within 24 hours prior to the visit, defined as a documented temperature of ≥37.3°C axillary/tympanic, ≥37.8°C orally, or ≥38.0°C rectally.
  • The primary cause of fever, as determined by the attending physician, is a respiratory tract infection.
  • Blood draw is required as part of standard clinical care.
  • Ability to comprehend the study's purpose, procedures, and potential risks, and willingness to provide written informed consent.

Критерии исключения

  • Inability to provide independent informed consent due to impaired consciousness or other reasons.
  • Inability to comply with the study procedures.
  • Medical contraindications to blood sampling, such as severe coagulopathy (e.g., INR > 3.0, platelet count < 50 × 10⁹/L).
  • Diagnosed with a terminal illness (e.g., advanced malignancy, severe multiple organ failure) and a life expectancy of less than 3 months.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения
Когортное

Центры проведения

Китай · 1 центр
  • Huadong hospital — Шанхай

Идентификаторы

NCT: NCT07278700 · FACTS

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗