A Study of Second- and Later-line Palliative Chemotherapy in Patients With Metastatic Colorectal Cancer.
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Second and later-line palliative chemotherapy.
- Кому может быть актуально
- Состояния в реестре: Metastatic Colorectal Cancer. Базовые параметры: от 19 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- South Korea
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
A Multi-center, Prospective, Observational Study to Assess the Treatment Patterns and Prognosis of Second and Later-line Palliative Chemotherapy in Patients With Metastatic Colorectal Cancer Who Failed First-line Palliative Chemotherapy
Обзор
This study aims to comprehensively identify the various treatment patterns of second- or subsequent-line palliative chemotherapy used in patients with metastatic colorectal cancer who have experienced failure of first-line palliative chemotherapy and to evaluate the prognosis of each treatment.
Вмешательства
- Препарат Second and later-line palliative chemotherapy
As this is a non-interventional study designed to collect data as part of routine clinical practice, the selection and dosage of medication, treatment period, and whether or not to change it are all based on the clinician's judgment
Первичные конечные точки
- Progression-free survival (PFS) [Срок оценки: up to 24 months]
Вторичные конечные точки (8)
- Overall Survival (OS) [Срок оценки: up to 24 months]
- Dosage period for each treatment pattern [Срок оценки: up to 24 months]
- Objective Response Rate (ORR) [Срок оценки: up to 24 months]
- Types of Secondary palliative chemotherapy [Срок оценки: up to 24 months]
- Types of Third palliative chemotherapy [Срок оценки: up to 24 months]
- Conversion rate [Срок оценки: up to 24 months]
- Quality of Life Assessment [Срок оценки: up to 12 months]
- Eastern Cooperative Oncology Group Performance Status(ECOG PS) Assessment [Срок оценки: up to 24 months]
Критерии участия
Критерии включения
- Patients who have signed the informed consent after receiving information about the purpose and method of this study.
- Patients with histologically and radiologically confirmed metastatic colorectal cancer (colorectal cancer) who have evaluable (measurable) lesions.
- Patients scheduled to receive their first second-line palliative chemotherapy following failure of first-line palliative chemotherapy (including those who relapse during or within 6 months after completion of postoperative adjuvant therapy, necessitating palliative chemotherapy).
- Patients who understand the research, are cooperative in the research process, and are deemed capable of participating until the completion date.
Критерии исключения
- Female patients who are pregnant, have childbearing potential, or are breastfeeding.
- Has received an investigational product within 4 weeks from the study enrollment or has plans to participate in another clinical trial during the participation of this study.
- Other subjects who are considered inappropriate to participate in this study by the judgment of the investigator.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
South Korea · 1 центр
- Samsung Medical Center — Seoul
Идентификаторы
NCT: NCT07263178 · BR-CPT-OS-402