Testing a Biometric Identification System to Improve Malaria Vaccine Completion

Обзор

Receiving all four doses of the malaria vaccine can significantly protect children against malaria illness, hospitalization, and death. However, in Ghana, only 46% of children complete the full vaccination sequence. More broadly, many children in Ghana do not receive the full set of recommended pediatric vaccinations. To address this, Simprints, in collaboration with Ghana Health Services, will implement a digital vaccination record system linked to biometrics. This system will automatically identify children who are behind on their vaccination schedule, providing health workers with information to prioritize community outreach. Additionally, it will send voice message reminders to caregivers to improve compliance. A cluster-randomized controlled trial (c-RCT) will be conducted in the Oti region to measure the impact of this innovation on the proportion of children completing malaria and routine vaccination schedules.

Вмешательства

• Поведенческое HEALTH FACILITY INTERVENTION
  Health facilities randomized in treatment clusters will be provided with a digital vaccination record system (e-tracker) linked to biometrics (facial recognition) of caregivers (if child is below 6 months) or of children (if child is above 6 months). With the support of Ghana Health Services, Simprints will train CHWs on digital vaccination record system (e-tracker) and biometrics. Simprints will also provide Technical Assistance to CHWs for the duration of the study.
• Поведенческое INDIVIDUAL INTERVENTION
  Caregivers (if child is below 6 months) or children (if child is above 6 months) living in communities in the catchment areas of health facilities randomized in treatment clusters will be registered at the community level into the e-tracker and biometrics (facial recognition), and caregivers of children who are due for or missed vaccination will receive voice message appointment reminders if they provided a phone number during the registration in biometrics. Reminders will be sent before a child

Первичные конечные точки

• Completion of full malaria sequence (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Timely full malaria vaccination (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Completion of full routine vaccination sequence (basic antigens) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Completion of full routine vaccination sequence (national schedule) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]

Вторичные конечные точки (12)

• Timely full routine vaccination sequence (basic antigens) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Timely full routine vaccination sequence (national schedule) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Early, Late or Very Late malaria vaccination (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Early, Late or Very Late full routine vaccination sequence (basic antigens) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Early, Late or Very Late full routine vaccination sequence (national schedule) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Number of malaria vaccines taken (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Number of routine vaccines taken (basic antigens) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Number of routine vaccines taken (full national schedule) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Number of timely malaria vaccines taken (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Number of timely routine vaccines taken (basic antigens) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Number of timely routine vaccines taken (full national schedule) (Index children) [Срок оценки: Measured at endline, 24-26 months after baseline]
• Received each vaccine on time (full national schedule) (Index child), analyzed individually [Срок оценки: Measured at endline, 24-26 months after baseline]

Критерии участия

Критерии включения

• Pregnant women (in the last two trimesters), aged 15-49 years old, who do not plan to permanently move in the next 12 months.
• Women with children under 6 months old, aged 15-49 years old, who do not plan to permanently move in the next 12 months.

Критерии исключения

• Non-age-eligible women.
• Men and non-emancipated minors.
• Women who do not consent.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Открытое

Основная цель

Организация здравоохранения

Центры проведения

Ghana · 1 центр

• Communities in Oti Region — Oti Region

Идентификаторы

NCT: NCT07261280 · HUM00270320

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗