Impact of Indoor Overheating on Physiological Strain in Children

Официальное название

A Preliminary Study Assessing the Effectiveness of a 26 °C Indoor Temperature Limit on Physiological Responses in Children

Обзор

Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children. Compared with adults, children are more susceptible to heat related illness due to less efficient thermoregulatory systems and difficulty recognizing early signs of heat stress. In addition, prolonged heat exposure can adversely affect their mental health, contributing to cognitive decline, heightened anxiety, and irritability. As children spend substantial time in hot environments at school and at home, and as these conditions intensify with climate change, actions to safeguard their health are essential. Yet our understanding of heat exposure effects in children remains incomplete, hindering the development of evidence based strategies to protect them. To address this gap, the investigators aim to evaluate whether an indoor temperature limit of 26 °C (45 percent relative humidity), the upper threshold recommended to protect older adults, can effectively prevent dangerous increases in physiological strain and declines in cognitive function in children during a simulated daylong heatwave. The preliminary study will assess physiological and cognitive responses in children aged 10 to 15 years during a 6 hour exposure (approximating a typical school day) to two conditions: (1) the recommended indoor temperature upper limit (26 °C) and (2) a high heat condition representative of homes and schools without air conditioning during extreme heat events (36 °C). In both conditions, children will remain seated at rest while wearing light clothing (t shirt and shorts), with the exception of performing 15 minutes of stepping exercise (6-6.5 METS) each hour (excluding the lunch period) to reflect typical daily activity in a school setting. This experimental design will allow investigators to determine whether maintaining indoor temperatures at the recommended upper limit for older adults sufficiently mitigates physiological strain in children.

Вмешательства

• Другое Simulated exposure to indoor overheating
  Children exposed to a 6-hour simulated heat exposure

Первичные конечные точки

• Core temperature (Peak) during daylong exposure to indoor overheating [Срок оценки: End of 6 hour daylong exposure]

Вторичные конечные точки (12)

• Profiles of Mood States (POMS) during daylong exposure to indoor overheating [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]
• Environmental Symptoms Questionnaire (ESQ) during daylong exposure to indoor overheating [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]
• Perceived exertion scale during daylong exposure to indoor temperature limit. [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]
• Activity levels during daylong exposure to indoor overheating [Срок оценки: End of 6 hour daylong exposure]
• Feel good scale during daylong exposure to indoor overheating [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]
• Thirst sensation scale during daylong exposure to indoor overheating [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]
• Thermal comfort scale during daylong exposure to indoor overheating [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]
• Thermal sensation 2 scale during daylong exposure to indoor overheating [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]
• Thermal sensation scale during daylong exposure to indoor overheating [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]
• Fluid loss during daylong exposure to indoor overheating [Срок оценки: At end of 6 hour daylong exposure]
• Fluid consumption during daylong exposure to indoor overheating [Срок оценки: At end of 6 hour daylong exposure]
• Hydration status during daylong exposure to indoor overheating [Срок оценки: At the start (hour 0) and end of 6 hour daylong exposure]

Критерии участия

Критерии включения

• English or French speaking.
• Ability to provide informed assent.

Критерии исключения

• Chronic health conditions
• Endurance exercise training (greater than 3 sessions of vigorous exercise training per week for 30 minutes or more)
• Restrictions to physical activity

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Перекрёстный дизайн

Маскирование

Простое слепое

Основная цель

Фундаментальное исследование

Центры проведения

Канада · 1 центр

• University of Ottawa — Ottawa

Идентификаторы

NCT: NCT07261202 · HEPRU-2025-10-A

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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