Набор по приглашению NCT07260318

Acute Effects of Cricket Fast Bowling on Bone Turnover and Signaling Markers

Без фазы С лечением Health Adults

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: Exercise.
Кому может быть актуально: Состояния в реестре: Health Adults. Базовые параметры: 18 лет — 30 лет · Мужчины.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Великобритания
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

The goal of this study is to investigate the acute effects of cricket fast bowling on the bone turnover and signaling markers in healthy young males. The main question aims to answer: • Does a single bout acute fast bowling change serum C-terminal telopeptide of type I collagen (CTX-I) and other bone turnover and signaling markers levels? Participants complete both the bowling and control trials, with a minimum washout period of one week between trials. During each trial, blood samples are collected at three time points: pre-, immediately post, and 2-hour post bowling/rest.

Вмешательства

Поведенческое Exercise
During the bowling trial, participants perform 8 sets of 6 deliveries (bowl at match intensity throughout), followed by 2-hour rest. Each set is interspersed by a 3-minute randomized fielding simulation. During the control trial, participants rest throughout instead of bowling.

Первичные конечные точки

Serum C-terminal telopeptide of type I collagen (CTX-I) concentration [Срок оценки: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]

Вторичные конечные точки (7)

Serum N-terminal propeptide of type I collagen (PINP) concentration [Срок оценки: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
Serum parathyroid hormone (PTH) concentration [Срок оценки: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
Serum sclerostin concentration [Срок оценки: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
Serum dickkopf Wnt signaling pathway inhibitor 1 (DKK1) concentration [Срок оценки: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
Serum osteoprotegerin (OPG) concentration [Срок оценки: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
Serum irisin concentration [Срок оценки: Blood samples are collected at baseline, immediately after the bowling or the corresponding rest period, and 2 hours after the second blood sample collection.]
Bowling speed [Срок оценки: Bowling speed is measured during the bowling trial.]

Критерии участия

Критерии включения

Healthy male
Aged 18 - 30
Cricket fast bowlers (a ball speed of \~100kmh) playing for a university team or above, such as British Universities and Colleges Sport (BUCS) or University Centre of Cricketing Excellence (UCCE)
Injury free for the last 3 months