Hospital- and Home-Based Structured Pulmonary Rehabilitation in Recently Admitted COPD Patients: A Quasi-Experimental Study at Assiut University

Официальное название

Evaluation of Three Months Combined Hospital and Home-Based Tailored Rehabilitation Program in COPD Patients Recently Admitted to Chest Department of Assiut University Hospital

Обзор

This study evaluates the effect of a structured three-month pulmonary rehabilitation (PR) program, delivered both in-hospital and at home, on exercise capacity, respiratory symptoms, and functional status in stable COPD patients.

Подробное описание

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of mortality and morbidity worldwide, significantly reducing patients' physical activity and quality of life. This study investigates a tailored pulmonary rehabilitation program combining hospital-based and home-based components over 12 weeks. The hospital component includes patient education, nutritional support, structured exercise training for both upper and lower limbs, and smoking cessation strategies. The home program emphasizes continuity with daily walking, strength exercises, and lifestyle modifications. The program aims to improve exercise capacity, dyspnea scores, and quality of life. Assessments include the six-minute walk test (6MWT), CAT score, mMRC dyspnea scale, spirometry, arterial blood gas analysis, and the St George's Respiratory Questionnaire. Measurements are collected at baseline and after program completion to assess improvements.

Вмешательства

• Поведенческое Pulmonary Rehabilitation
  A tailored pulmonary rehabilitation program combining hospital-based and home-based components over 12 weeksParticipants undergo a 12-week structured PR program including both hospital-based sessions (education, structured exercise, nutrition counseling, smoking cessation) and home-based exercises (daily walking, strength training progression

Первичные конечные точки

• Six-Minute Walk Test (6MWT) [Срок оценки: 12 weeks]

Критерии участия

Критерии включения

• Stable COPD patients diagnosed based on spirometry (post-bronchodilator FEV1/FVC <70%)

Age > 40 years

Moderate to severe COPD stage

Able and willing to participate in rehabilitation program

Критерии исключения

• Age < 40 years

Current acute COPD exacerbation at enrollment

Significant comorbid conditions limiting participation (e.g., uncontrolled diabetes mellitus, uncontrolled hypertension, left-sided heart failure, renal failure, liver cell failure)

Neuromuscular diseases, severe cognitive impairment, or psychiatric disturbance

Pregnant patients

Unwilling to participate in the rehabilitation program

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Не применимо

Модель

Одна группа

Маскирование

Открытое

Основная цель

Лечение

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Публикации

• Arnold MT, Dolezal BA, Cooper CB. Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease: Highly Effective but Often Overlooked. Tuberc Respir Dis (Seoul). 2020 Oct;83(4):257-267. doi: 10.4046/trd.2020.0064. Epub 2020 Aug 10. PMID 32773722

Идентификаторы

NCT: NCT07197229 · Combined Pulmonary Rehabilitat

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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