Valvular Heart Disease in Women Registry
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- Это наблюдательное исследование: исследуемое лечение участникам по протоколу не назначают.
- Кому может быть актуально
- Состояния в реестре: Valve Disease, Heart, Gender Bias, Guideline Adherence, Guideline Implementation. Базовые параметры: от 18 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Египет, Португалия
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Обзор
Valvular heart disease (VHD) is a major global health issue. Untreated rheumatic heart disease persists in many regions, preventable with timely care. Higher-income countries face rising calcific valve disease from aging, worsened by VHD complications, like infective endocarditis, resulting in higher morbidity/mortality. Gender disparities in VHD remains understudied, despite inequalities in risks, diagnosis, and treatment. Prevalence varies by gender, but uneven diagnostics and therapies obscure realities. This registry will examine gender disparities from hospital admission to first outpatient follow-up, recruiting both men and women to investigate and report the study objectives.
Подробное описание
Valvular heart disease (VHD) is a major global public health problem (1). Many regions of the world continue to grapple with the adverse consequences of untreated rheumatic heart disease, a condition that is largely preventable with timely access to diagnosis and treatment (2, 3). In turn, middle- and high-income countries have experienced a rise in the prevalence of calcific aortic and mitral disease, owing in part to population ageing (3). This public health problem is further compounded by high rates of infective endocarditis, which is associated with substantial morbidity and mortality. Yet, considerations of gender disparities have not taken centre stage in VHD research. This is despite evidence of major healthcare disparities in socioeconomic and medical risk factors, access to diagnosis, and provision of appropriate treatment (4-7). The prevalence of VHD varies by gender, but diagnostic evaluations are not equitable across the groups, which makes the true prevalence less clear. The delivery of evidence-based treatments for VHD is not equitable (8). The aim of this registry will be to examine gender differences in VHD from the time point of admission to the hospital (either elective or urgent admission) up to the first follow-up in an outpatient clinic. We will recruit both men and women in order to analyse the gender disparities.
Первичные конечные точки
- Disparities in Valvular Heart Disease (VHD) Treatment [Срок оценки: One year]
- Disparities in Valvular Heart Disease Management [Срок оценки: One year]
- Adherence to/Compliance with European Society of Cardiology (ESC) Guidelines for Management of Valvular Heart Disease. [Срок оценки: One Year]
Вторичные конечные точки (3)
- Time from Diagnosis to Guideline-Directed Therapy: Comparison Between Women and Men [Срок оценки: One Year]
- Time from Symptom Onset to Presentation at Tertiary Center: Comparison Between Women and Men [Срок оценки: One Year]
- Procedural Complications: Comparison Between Women and Men [Срок оценки: One Year]
Критерии участия
Критерии включения
- Adult patients with diagnosis of any VHD according to the current ESC guidelines.
- Admission to the VHD-W Registry collaborating center.
Критерии исключения
- Age less than 18 years old.
- Inability to provide informed consent per local institutional and regulatory requirements.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Модель наблюдения
- Другое
Центры проведения
Египет · 1 центр
- Aswan Heart Centre — Aswān
Португалия · 1 центр
- University of Lisbon — Lisbon
Идентификаторы
NCT: NCT07196930 · VHD-W Registry